Research Review: What we have learned about the causes of eating disorders–a synthesis of sociocultural, psychological, and biological research

KM Culbert, SE Racine… - Journal of child psychology …, 2015 - Wiley Online Library
Background Eating disorders are severe psychiatric disorders with a complex etiology
involving transactions among sociocultural, psychological, and biological influences. Most …

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

Brain-derived neurotrophic factor, food intake regulation, and obesity

H Rosas-Vargas, JD Martínez-Ezquerro… - Archives of medical …, 2011 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a fundamental role in
development and plasticity of the central nervous system (CNS). It is currently recognized as …

Recent advances in developmental and risk factor research on eating disorders

JL Bakalar, LM Shank, A Vannucci, RM Radin… - Current psychiatry …, 2015 - Springer
Abstract The Diagnostic and Statistical Manual of Mental Disorders (ie, DSM-5) currently
recognizes three primary eating disorders: anorexia nervosa, bulimia nervosa, and binge …

DNA methylation in individuals with anorexia nervosa and in matched normal‐eater controls: A genome‐wide study

L Booij, KF Casey, JM Antunes, M Szyf… - … Journal of Eating …, 2015 - Wiley Online Library
Objective Evidence associates anorexia nervosa (AN) with epigenetic alterations that could
contribute to illness risk or entrenchment. We investigated the extent to which AN is …

The brain‐derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar …

S Bonaccorso, M Sodhi, J Li, WV Bobo… - Bipolar …, 2015 - Wiley Online Library
Objectives We tested the hypothesis that a common functional variant in brain‐derived
neurotrophic factor (BDNF), Val66Met, which has been shown to be associated with …

Association between brain-derived neurotrophic factor Val66Met and obesity in children and adolescents

M Skledar, M Nikolac, K Dodig-Curkovic… - Progress in Neuro …, 2012 - Elsevier
Obesity in children and adolescents is a worldwide health problem, characterized by various
somatic, psychosocial and psychiatric complications, and is often associated with adult …

A systematic review and secondary data analysis of the interactions between the serotonin transporter 5-HTTLPR polymorphism and environmental and psychological …

V Rozenblat, D Ong, M Fuller-Tyszkiewicz… - Journal of psychiatric …, 2017 - Elsevier
Objectives To summarize and synthesize the growing gene x environment (GxE) research
investigating the promoter region of the serotonin transporter gene (5-HTTLPR) in the eating …

Disentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation

GM Leyden, MP Greenwood, V Gaborieau… - British Journal of …, 2023 - nature.com
Background Body mass index (BMI) is known to influence the risk of various site-specific
cancers, however, dissecting which subcomponents of this heterogenous risk factor are …

The impact of adverse life events and the serotonin transporter gene promoter polymorphism on the development of eating disorder symptoms

K Akkermann, K Kaasik, E Kiive, N Nordquist… - Journal of psychiatric …, 2012 - Elsevier
Adverse life events have been shown to predict weight fluctuations and dietary restraint, as
well as eating disorders during adolescence or early adulthood. Since the s-allele carriers of …