The relationship between metabolism and cell cycle progression is complex and
bidirectional. Cells must rewire metabolism to meet changing biosynthetic demands across …

Mitosis ensures genome integrity by mediating precise segregation of the duplicated genetic
material. Segregation of subcellular organelles during mitosis also needs to be tightly …

Cells adopt a size that is optimal for their function, and pushing them beyond this limit can
cause cell aging and death by senescence or reduce proliferative potential. However, by …

Recent experiments suggested that ATP can effectively stabilize protein structure and inhibit
protein aggregation when its concentration is less than 10 mM, which is significantly lower …

Cell mass and composition change with cell cycle progression. Our previous work
characterized buoyant mass dynamics in mitosis (Miettinen et al., 2019), but how dry mass …

The study of metabolism is undergoing a renaissance. Since the year 2002, over 50
genetically-encoded fluorescent indicators (GEFIs) have been introduced, capable of …

Many cellular condensates are heterotypic mixtures of proteins and RNA formed in complex
environments. Magnesium ions (Mg 2+) and ATP can impact RNA folding, and local …

Chemical derivatives of polyethylenimine (PEI) receptors with either triphenylamine (TPA) or
7-hydroxy-4-methyl-coumarin (Cou) form stable complexes with adenine and guanine …

While we have a solid understanding of the cell biological and biochemical control aspects
of the eukaryotic cell growth and division process, much less is known about the metabolic …

Background: Diabetic retinopathy (DR) is one of the most important microvascular diseases
of diabetes. Our previous research demonstrated that bile acid G-protein-coupled …