Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention
S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
microRNA regulation of inflammatory responses
RM O'Connell, DS Rao… - Annual review of …, 2012 - annualreviews.org
The mammalian inflammatory response is a rapid and complex physiological reaction to
noxious stimuli including microbial pathogens. Although inflammation plays a valuable role …
noxious stimuli including microbial pathogens. Although inflammation plays a valuable role …
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DS Cunninghame Graham… - Nature …, 2015 - nature.com
Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease
characterized by loss of immune tolerance to nuclear and cell surface antigens. Previous …
characterized by loss of immune tolerance to nuclear and cell surface antigens. Previous …
MicroRNA-146a: a dominant, negative regulator of the innate immune response
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that can play critical
roles as regulators of numerous pathways and biological processes including the immune …
roles as regulators of numerous pathways and biological processes including the immune …
MicroRNAs in common human diseases
Y Li, KV Kowdley - Genomics, Proteomics and Bioinformatics, 2012 - academic.oup.com
MicroRNAs (miRNAs) are a class of short non-coding RNA molecules that have attracted
tremendous attention from the biological and biomedical research communities over the …
tremendous attention from the biological and biomedical research communities over the …
Immunogenetics of systemic lupus erythematosus: a comprehensive review
Y Ghodke-Puranik, TB Niewold - Journal of autoimmunity, 2015 - Elsevier
Our understanding of the genetic basis of systemic lupus erythematosus has progressed
rapidly in recent years. While many genetic polymorphisms have been associated with …
rapidly in recent years. While many genetic polymorphisms have been associated with …
[HTML][HTML] Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease
It has been found that the majority of disease-associated genetic variants identified by
genome-wide association studies are located outside of protein-coding regions, where they …
genome-wide association studies are located outside of protein-coding regions, where they …
Update on the genetics of systemic lupus erythematosus: genome-wide association studies and beyond
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …
that primarily affects women of childbearing age. The development of SLE is attributed to the …
The role of microRNAs in human diseases
KU Tüfekci, MG Öner, RLJ Meuwissen… - … : MicroRNA biology and …, 2014 - Springer
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now
microRNAs are implicated in a variety of physiological and pathological processes. Since …
microRNAs are implicated in a variety of physiological and pathological processes. Since …
Contribution of MicroRNAs to autoimmune diseases
LP Garo, G Murugaiyan - Cellular and Molecular Life Sciences, 2016 - Springer
MicroRNAs are a class of evolutionarily conserved, short non-coding RNAs that post-
transcriptionally modulate the expression of multiple target genes. They are implicated in …
transcriptionally modulate the expression of multiple target genes. They are implicated in …