The review presented here lays out the present state of the art in the field of radionuclide
therapies specifically targeted against the nucleus of cancer cells, focussing on the use of …

Background Tumor hypoxia (low tissue oxygenation) is an adverse condition of the solid
tumor environment, associated with malignant progression, radiotherapy resistance, and …

Our objective was to evaluate the biodistribution, kinetics, and radiation dosimetry of
64CuCl2 in humans and to assess the ability of 64CuCl2 PET/CT to detect prostate cancer …

Purpose The present review article aims to provide an overview of the available
radionuclides for palliative treatment of bone metastases beyond 89 Sr and 153 Sm. In …

The presence of Auger electrons (AE) among the decay products of a number of
radionuclides makes these radionuclides an attractive means for treating cancer because …

Thulium-167 is a promising radionuclide for nuclear medicine applications with potential use
for both diagnosis and therapy (“theragnostics”) in disseminated tumor cells and small …

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults
with a median survival time less than one year. To date, there are only a limited number of …

Purpose Hypoxic tumors are associated with therapy resistance and poor cancer prognosis,
but methods to detect and counter tumor hypoxia remain insufficient. Our purpose was to …

We present the combination of the clinically well-proven chemotherapeutic agent,
Doxorubicin, and 99mTc, an Auger and internal conversion electron emitter, into a dual …

Presented are the results of 99mTc and 101Tc production via neutron irradiation of natural
isotopic molybdenum (Mo) with epithermal/resonance neutrons. Neutrons were produced …