In the last decades, the easy genetic manipulation, the external fertilization, the high
percentage of homology with human genes and the reduced husbandry costs compared to …

Processes that regulate size and patterning along an axis must be highly integrated to
generate robust shapes; relative changes in these processes underlie both congenital …

Osteogenesis imperfecta (OI) is a family of rare heritable skeletal disorders associated with
dominant mutations in the collagen type I encoding genes and recessive defects in proteins …

Fin regeneration has been extensively studied in zebrafish, a genetic model organism. Little
is known about regulators of this process in distant fish taxa, such as the Poeciliidae family …

Collagen fibers provide physical support to animal tissues by orienting in the correct position
and at optimal density. Actinotrichia are thick collagen fibers that are present at the tips of …

Abstract Background The gene cAMP‐Responsive Element Binding protein 3‐like‐1
(CREB3L1) has been implicated in bone development in mice, with CREB3L1 knock‐out …

Objectives Bone tissue in bony fish demonstrates a remarkable ability to regenerate,
particularly evident following induction of extensive bone defects, such as fin amputation …

Fraser Syndrome is a rare, multisystemic autosomal recessive disorder characterized by
disrupted epithelial-mesenchymal associations upon loss of Fraser Complex genes …

The fins of fishes are remarkably diverse, and this variation is tied to the ecology and
locomotor mode of a species. While numerous genetic factors are known to pattern fins in …

Appendage shape is formed during development (and re-formed during regeneration)
according to spatial and temporal cues that orchestrate local cellular morphogenesis. The …