Asthma remission: what is it and how can it be achieved?

D Thomas, VM McDonald, ID Pavord… - European Respiratory …, 2022 - Eur Respiratory Soc
Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases

I Agache, CA Akdis - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
A rapidly developing paradigm for modern health care is a proactive and individualized
response to patients' symptoms, combining precision diagnosis and personalized treatment …

[HTML][HTML] Characterization of severe asthma worldwide: data from the International Severe Asthma Registry

E Wang, ME Wechsler, TN Tran, LG Heaney, RC Jones… - Chest, 2020 - Elsevier
Background Clinical characteristics of the international population with severe asthma are
unknown. Intercountry comparisons are hindered by variable data collection within regional …

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report

VM McDonald, J Fingleton, A Agusti… - European …, 2019 - publications.ersnet.org
“Treatable traits” have been proposed as a new paradigm for the management of airway
diseases, particularly complex disease, which aims to apply personalised medicine to each …

When to consider lung transplantation for COVID-19

M Cypel, S Keshavjee - The Lancet Respiratory Medicine, 2020 - thelancet.com
Several respiratory viruses are known to cause acute respiratory distress syndrome (ARDS).
Survival and lung recovery rates are well known for influenza viruses; however, ARDS …

[HTML][HTML] Clinical remission in severe asthma with biologic therapy: an analysis from the UK Severe Asthma Registry

PJ McDowell, R McDowell, J Busby… - European …, 2023 - Eur Respiratory Soc
Background Novel biologic therapies have revolutionised the management of severe
asthma with more ambitious treatment aims. Here we analyse the definition of clinical …

Treatable traits in airway disease: from theory to practice

A Agusti, PG Gibson, VM McDonald - The Journal of Allergy and Clinical …, 2023 - Elsevier
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are
prevalent and complex conditions that often coexist in the same patient. To address this …

Treatable traits in the NOVELTY study

A Agustí, E Rapsomaniki, R Beasley, R Hughes… - …, 2022 - Wiley Online Library
Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …

Associations of symptoms of anxiety and depression with health-status, asthma control, dyspnoea, dysfunction breathing and obesity in people with severe asthma

MA Stubbs, VL Clark, PG Gibson, J Yorke… - Respiratory …, 2022 - Springer
Background Anxiety and depression are comorbidities of severe asthma. However, clinical
characteristics associated with coexisting severe asthma and anxiety/depression are poorly …

Mechanisms and management of asthma exacerbations

JM Ramsahai, PM Hansbro… - American Journal of …, 2019 - atsjournals.org
Acute asthma remains an important medical emergency, the most frequent cause of acute
admissions in children and a major source of morbidity for adults with asthma. In all ages …