Simple Summary Some regions of aggressive malignancies experience hypoxia due to
inadequate blood supply. Cancer cells adapting to hypoxic conditions somehow become …

Purpose The aim of this work is to review the published studies on radiation resistance
mechanisms and molecular markers involved in different tumors. The revision has been …

Background Heat shock protein beta-1 (HSPB1) is a crucial biomarker for pathological
processes in various cancers. However, the clinical value and function of HSPB1 in breast …

The tumor microenvironment (TME) promotes the malignant transformation of cancer cells,
mainly through metabolic reprogramming. As one of the most prominent features of the TME …

Glioblastoma multiforme (GBM) is an aggressive cancer without currently effective therapies.
Radiation and temozolomide (radio/TMZ) resistance are major contributors to cancer …

Glioblastoma (GBM) is the most malignant and aggressive primary brain tumor and is highly
resistant to current therapeutic strategies. Previous studies have demonstrated that reactive …

The transcription factor Friend leukemia virus integration 1 (Fli-1) belonging to the E26
Transformation-Specific (ETS) transcription factor family is not only expressed in normal …

Background Radiotherapy resistance is the main cause of treatment failure in
nasopharyngeal carcinoma (NPC), which leads to poor prognosis. It is urgent to elucidate …

Fusion genes are abnormal genes resulting from chromosomal translocation, insertion,
deletion, inversion, etc. ETV6, a rather promiscuous partner forms fusions with several other …

Despite clinical and epidemiological evidence suggestive of a link between glioblastoma
(GBM) and periodontitis (PD), the shared mechanisms of gene regulation remain elusive. In …