Advanced glycation end products (AGEs) are potentially harmful and heterogeneous
molecules derived from nonenzymatic glycation. The pathological implications of AGEs are …

Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …

Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …

Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …

Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …

Oxidative stress plays an important role in the pathogenesis of various chronic liver diseases
(CLD) and increasing evidence have confirmed the contributory role of oxidative stress in …

CYP2E1 is one of the fifty-seven cytochrome P450 genes in the human genome and is
highly conserved. CYP2E1 is a unique P450 enzyme because its heme iron is constitutively …

Diabetes mellitus is a non-communicable disease that occurs in both developed and
developing countries. This metabolic disease affects all systems in the body, including the …

Alcoholic liver disease (ALD) has been among the leading causes of cirrhosis and liver-
related death worldwide for decades. Early discoveries in alcoholic liver disease identified …

Liver fibrosis, as an excess deposition of extracellular matrix (ECM) components, results
from chronic liver injury as well as persistent activation of inflammatory response and of …