In the last decades, it has been demonstrated that marine organisms are a substantial
source of bioactive compounds with possible biotechnological applications. Marine …

Metabolomics represent the set of small organic molecules generally called metabolites,
which are located within cells, tissues or organisms. This new “omic” technology, together …

Chronic wounds, such as diabetic foot ulcers (DFU), are a serious clinical problem. It is a
challenge for the conventional wound dressings to achieve the desirable therapeutic …

Nine new isomalabaricane terpenoids (1–9) were isolated from the sponge Rhabdastrella
globostellata of Ximao Island, together with 13 known ones (10–22). The structures were …

Marine sponges associated microorganisms are considered to be prolific source of bioactive
natural products. Omics-based techniques such as metagenomics and metatranscriptomics …

Sponges are a vital source of pharmaceutically active secondary metabolites, of which the
main structural types are alkaloids and terpenoids. Many of these compounds exhibit …

The waters around the western Antarctic Peninsula are experiencing fast warming due to
global change, being among the most affected regions on the planet. This polar area is …

The asymmetric γ‐regioselective‐alkylation reaction which is catalyzed by a chiral tertiary
amine ((DHQ) 2PHAL) and takes advantage of isatin‐derived Morita‐Baylis‐Hillman …

Abstract The Red Sea is a promising habitat for the discovery of new bioactive marine
natural products. Sponges associated microorganisms represent a wealthy source of …

The transferrin receptor 1 (TfR1) plays a key role in cellular iron uptake through its
interaction with iron-bound Tf. TfR1 is often reported to be overexpressed in malignant cells …