Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment

S Lampsas, M Xenou, E Oikonomou, P Pantelidis… - Molecules, 2023 - mdpi.com
Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …

Existing and emerging strategies to lower Lipoprotein (a)

GG Schwartz, CM Ballantyne - Atherosclerosis, 2022 - Elsevier
Abundant evidence links elevated levels of lipoprotein (a)(Lp (a)) to higher cardiovascular
risk, leaving clinicians with the challenge of what measures to take to mitigate Lp (a) …

[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021

M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

[HTML][HTML] Lipoprotein (a) levels from childhood to adulthood: data in nearly 3,000 children who visited a pediatric lipid clinic

LM de Boer, MH Hof, A Wiegman, AK Stroobants… - Atherosclerosis, 2022 - Elsevier
Background and aims Elevated lipoprotein (a)[Lp (a)] is an independent risk factor for
cardiovascular disease. In clinical practice, Lp (a) is mostly measured only once assuming …

Step‐by‐step diagnosis and management of the nocebo/drucebo effect in statin‐associated muscle symptoms patients: a position paper from the International Lipid …

PE Penson, E Bruckert, D Marais… - Journal of cachexia …, 2022 - Wiley Online Library
Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with
statin therapy [most commonly statin‐associated muscle symptoms (SAMS)] result in the …

A focused update to the 2019 NLA scientific statement on use of lipoprotein (a) in clinical practice

ML Koschinsky, A Bajaj, MB Boffa, DL Dixon… - Journal of clinical …, 2024 - Elsevier
Since the 2019 National Lipid Association (NLA) Scientific Statement on Use of Lipoprotein
(a) in Clinical Practice was issued, accumulating epidemiological data have clarified the …

Lp (a): a new pathway to target?

NS Nurmohamed, JM Kraaijenhof… - Current Atherosclerosis …, 2022 - Springer
Abstract Purpose of Review Over the past decades, genetic and observational evidence has
positioned lipoprotein (a) as novel important and independent risk factor for cardiovascular …

Atherogenic lipoproteins for the statin residual cardiovascular disease risk

H Yanai, H Adachi, M Hakoshima… - International journal of …, 2022 - mdpi.com
Randomized controlled trials (RCTs) show that decreases in low-density lipoprotein
cholesterol (LDL-C) by the use of statins cause a significant reduction in the development of …

Novel pharmacological therapies for the management of hyperlipoproteinemia (a)

CE Kosmas, MD Bousvarou… - International Journal of …, 2023 - mdpi.com
Lipoprotein (a)[Lp (a)] is a well-established risk factor for cardiovascular disease,
predisposing to major cardiovascular events, including coronary heart disease, stroke, aortic …

Role of lipoprotein (a) in atherosclerotic cardiovascular disease: A review of current and emerging therapies

IS Alhomoud, A Talasaz, A Mehta… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Lipoprotein (a), or Lp (a), is structurally like low‐density lipoprotein (LDL) but differs
in that it contains glycoprotein apolipoprotein (a)[apo (a)]. Due to its prothrombotic and …