Protein lipidation dramatically affects protein structure, localization, and trafficking via
remodeling protein–membrane and protein–protein interactions through hydrophobic lipid …

Abstract Sirtuins (SIRT1-SIRT7), a family of nicotinamide adenine dinucleotide (NAD+)-
dependent enzymes, are key regulators of life span and metabolism. In addition to acting as …

The Golgi apparatus modifies and transports secretory and membrane proteins. In some
instances, the production of secretory and membrane proteins exceeds the capacity of the …

The Golgi apparatus is an essential cellular organelle that mediates homeostatic functions,
including vesicle trafficking and the post-translational modification of macromolecules. Its …

Cardiovascular diseases (CVDs) can be described as a global health emergency imploring
possible prevention strategies. Although the pathogenesis of CVDs has been extensively …

Escape from the bacterial-containing vacuole (BCV) is a key step of Shigella host cell
invasion. Rab GTPases subverted to in situ-formed macropinosomes in the vicinity of the …

Silent information regulators (sirtuins) are highly evolutionarily conserved and participate in
many biological processes in the human body. Unlike classical histone deacetylases, the …

Background Sepsis is a life-threatening condition involving organ dysfunction characterized
by a generalized inflammatory syndrome, and the associated mortality rate is high …

Background Identification of non-sputum diagnostic markers for tuberculosis (TB) is urgently
needed. This exploratory study aimed to discover potential serum protein biomarkers for the …

Campylobacteriosis, the foodborne disease caused by Campylobacter spp., infects one out
of 10 individuals every year. C. jejuni accounts for 90% of these infections resulting in …