[HTML][HTML] The role of selenium in pathologies: an updated review

G Barchielli, A Capperucci, D Tanini - Antioxidants, 2022 - mdpi.com
Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Hashimoto's thyroiditis: An update on pathogenic mechanisms, diagnostic protocols, therapeutic strategies, and potential malignant transformation

M Ralli, D Angeletti, M Fiore, V D'Aguanno… - Autoimmunity …, 2020 - Elsevier
Hashimoto's thyroiditis, characterized by thyroid-specific autoantibodies, is one of the
commonest autoimmune disorders. Although the exact etiology has not been fully …

Selenium in thyroid disorders—essential knowledge for clinicians

KH Winther, MP Rayman, SJ Bonnema… - Nature Reviews …, 2020 - nature.com
In the 1990s, selenium was identified as a component of an enzyme that activates thyroid
hormone; since this discovery, the relevance of selenium to thyroid health has been widely …

Selenium and human health

MP Rayman - The Lancet, 2012 - thelancet.com
Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects,
ranging from antioxidant and anti-inflammatory effects to the production of active thyroid …

Selenium: an element for life

LH Duntas, S Benvenga - Endocrine, 2015 - Springer
This review aims to illustrate the importance of selenium (Se) for maintenance of overall
health, especially for the thyroid, immunity, and homeostasis. Furthermore, it outlines the …

The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities

Z Huang, AH Rose, PR Hoffmann - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Dietary selenium (] Se), mainly through its incorporation into selenoproteins, plays
an important role in inflammation and immunity. Adequate levels of Se are important for …

Association of depression and anxiety disorders with autoimmune thyroiditis: a systematic review and meta-analysis

EM Siegmann, HHO Müller, C Luecke… - JAMA …, 2018 - jamanetwork.com
Importance With a prevalence of 4% to 13% in the United States, autoimmune thyroiditis
(AIT) is a major health problem. Besides somatic complications, patients with AIT can also …

Low population selenium status is associated with increased prevalence of thyroid disease

Q Wu, MP Rayman, H Lv, L Schomburg… - The Journal of …, 2015 - academic.oup.com
Context: Epidemiological studies have supported the premise that an adequate selenium
intake is essential for thyroid gland function. Objective: The objective was to investigate …

Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association

JR Garber, RH Cobin, H Gharib, JV Hennessey, I Klein… - Thyroid, 2012 - liebertpub.com
Background: Hypothyroidism has multiple etiologies and manifestations. Appropriate
treatment requires an accurate diagnosis and is influenced by coexisting medical conditions …

[HTML][HTML] The pathogenesis of Hashimoto's thyroiditis: further developments in our understanding

RA Ajjan, AP Weetman - Hormone and Metabolic Research, 2015 - thieme-connect.com
Hashimoto's thyroiditis (HT) is part of a spectrum of thyroid autoimmune conditions and this
review provides an update on the latest developments in the field. HT has a genetic …