Prognostic and predictive molecular biomarkers for colorectal cancer: updates and challenges
E Koncina, S Haan, S Rauh, E Letellier - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death among cancer patients. This
heterogeneous disease is characterized by alterations in multiple molecular pathways …
heterogeneous disease is characterized by alterations in multiple molecular pathways …
Identifying significantly impacted pathways: a comprehensive review and assessment
Background Many high-throughput experiments compare two phenotypes such as disease
vs. healthy, with the goal of understanding the underlying biological phenomena …
vs. healthy, with the goal of understanding the underlying biological phenomena …
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Abstract FlyAtlas 2 (www. flyatlas2. org) is part successor, part complement to the FlyAtlas
database and web application for studying the expression of the genes of Drosophila …
database and web application for studying the expression of the genes of Drosophila …
Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients.
B Győrffy, A Lánczky, Z Szállási - Endocrine-related cancer, 2012 - real.mtak.hu
The validation of prognostic biomarkers in large independent patient cohorts is a major
bottleneck in ovarian cancer research. We implemented an online tool to assess the …
bottleneck in ovarian cancer research. We implemented an online tool to assess the …
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
Validating prognostic or predictive candidate genes in appropriately powered breast cancer
cohorts are of utmost interest. Our aim was to develop an online tool to draw survival plots …
cohorts are of utmost interest. Our aim was to develop an online tool to draw survival plots …
Synovial tissue research: a state-of-the-art review
The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …
arthritis. The study of synovial tissue has advanced considerably throughout the past few …
Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications
ZC Hartman, DM Appledorn, A Amalfitano - Virus research, 2008 - Elsevier
Extensively characterized, modified, and employed for a variety of purposes, adenovirus
(Ad) vectors are generally regarded as having great potential by many applied virologists …
(Ad) vectors are generally regarded as having great potential by many applied virologists …
Breast cancer metastasis: markers and models
B Weigelt, JL Peterse, LJ Van't Veer - Nature reviews cancer, 2005 - nature.com
Breast cancer starts as a local disease, but it can metastasize to the lymph nodes and distant
organs. At primary diagnosis, prognostic markers are used to assess whether the transition …
organs. At primary diagnosis, prognostic markers are used to assess whether the transition …
Comparative analysis of proteome and transcriptome variation in mouse
The relationships between the levels of transcripts and the levels of the proteins they encode
have not been examined comprehensively in mammals, although previous work in plants …
have not been examined comprehensively in mammals, although previous work in plants …
Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior
MM Halassa, PG Haydon - Annual review of physiology, 2010 - annualreviews.org
The past decade has seen an explosion of research on roles of neuron-astrocyte
interactions in the control of brain function. We highlight recent studies performed on the …
interactions in the control of brain function. We highlight recent studies performed on the …