Invasive bacteria actively induce their own uptake by phagocytosis in normally
nonphagocytic cells and then either establish a protected niche within which they survive …

Lamellipodia, filopodia and membrane ruffles are essential for cell motility, the organization
of membrane domains, phagocytosis and the development of substrate adhesions. Their …

A sudden increase in permeability of the inner mitochondrial membrane, the so-called
mitochondrial permeability transition, is a common feature of apoptosis and is mediated by …

The initial stages of animal virus infection are generally described as the binding of free
virions to permissive target cells followed by entry and replication. Although this route of …

Cortactin fulfills many functions in various cell types. These functions have been considered
to derive from its ability to activate the Actin-related protein 2/3 (Arp2/3) complex, and are …

Actin polymerization often occurs at the plasma membrane to drive the protrusion of
lamellipodia and filopodia at the leading edge of migrating cells. A role for actin …

Simian virus 40 (SV40) utilizes endocytosis through caveolae for infectious entry into host
cells. We found that after binding to caveolae, virus particles induced transient breakdown of …

The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and
ARPC1–5) and plays an essential role in generating branched actin filament networks …

Synapses are highly specialized intercellular junctions that mediate the transmission of
information between axons and target cells. A fundamental property of synapses is their …

The life cycle of most viruses involves the release of particles into the extracellular space.
Consequently, the study of virus egress as well as virus entry has focused almost exclusively …