Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization

S Hua, MBC De Matos, JM Metselaar… - Frontiers in …, 2018 - frontiersin.org
The use of nanotechnology in medicine has the potential to have a major impact on human
health for the prevention, diagnosis, and treatment of diseases. One particular aspect of the …

Silver nanoparticles: Significance of physicochemical properties and assay interference on the interpretation of in vitro cytotoxicity studies

KBR Ahmed, AM Nagy, RP Brown, Q Zhang… - Toxicology in Vitro, 2017 - Elsevier
Silver nanoparticles (AgNPs) have generated a great deal of interest in the research,
consumer product, and medical product communities due to their antimicrobial and anti …

Towards FAIR nanosafety data

N Jeliazkova, MD Apostolova, C Andreoli… - Nature …, 2021 - nature.com
Nanotechnology is a key enabling technology with billions of euros in global investment
from public funding, which include large collaborative projects that have investigated …

[HTML][HTML] In vitro approaches to assess the hazard of nanomaterials

B Drasler, P Sayre, KG Steinhäuser, A Petri-Fink… - NanoImpact, 2017 - Elsevier
The rapid development of engineered nanomaterials demands for a fast and reliable
assessment of their health hazard potential. A plethora of experimental approaches have …

The alamar blue assay in the context of safety testing of nanomaterials

EM Longhin, N El Yamani, E Rundén-Pran… - Frontiers in …, 2022 - frontiersin.org
The Alamar Blue (AB) assay is widely used to investigate cytotoxicity, cell proliferation and
cellular metabolic activity within different fields of toxicology. The use of the assay with …

Bio-conjugated quantum dots for cancer research: detection and imaging

Z Liang, MB Khawar, J Liang, H Sun - Frontiers in Oncology, 2021 - frontiersin.org
Ultrasound, computed tomography, magnetic resonance, and gamma scintigraphy-based
detection and bio-imaging technologies have achieved outstanding breakthroughs in recent …

A One Health approach to managing the applications and implications of nanotechnologies in agriculture

E Lombi, E Donner, M Dusinska, F Wickson - Nature Nanotechnology, 2019 - nature.com
The need for appropriate science and regulation to underpin nanosafety is greater than ever
as ongoing advances in nanotechnology are rapidly translated into new industrial …

High throughput toxicity screening and intracellular detection of nanomaterials

AR Collins, B Annangi, L Rubio… - Wiley …, 2017 - Wiley Online Library
With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and
reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical …

[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - Food and Chemical …, 2017 - Elsevier
The unique properties of nanomaterials (NMs) are beneficial in numerous industrial and
medical applications. However, they could also induce unintended effects. Thus, a proper …

Precision nanotoxicology in drug development: Current trends and challenges in safety and toxicity implications of customized multifunctional nanocarriers for drug …

A Ahmad, M Imran, N Sharma - Pharmaceutics, 2022 - mdpi.com
The dire need for the assessment of human and environmental endangerments of
nanoparticulate material has motivated the formulation of novel scientific tools and …