Advancement in cancer stem cell biology and precision medicine—review article head and neck cancer stem cell plasticity and the tumor microenvironment

ME Heft Neal, JC Brenner, MEP Prince… - Frontiers in Cell and …, 2022 - frontiersin.org
Head and Neck cancer survival has continued to remain around 50% despite treatment
advances. It is thought that cancer stem cells play a key role in promoting tumor …

Identification of latent biomarkers in connection with progression and prognosis in oral cancer by comprehensive bioinformatics analysis

A Reyimu, Y Chen, X Song, W Zhou, J Dai… - World Journal of Surgical …, 2021 - Springer
Background Oral cancer (OC) is a common and dangerous malignant tumor with a low
survival rate. However, the micro level mechanism has not been explained in detail …

CircPVT1 promotes the tumorigenesis and metastasis of osteosarcoma via mediation of miR-26b-5p/CCNB1 axis

SX Huang, HB Mei, K Liu, J Tang, JY Wu… - Journal of Bone and …, 2022 - Springer
Introduction Osteosarcoma (OS) is the most aggressive malignancy among the bone tumors
in the world. Circular RNAs (circRNAs) have been reported to be participated in multiple …

Hsa_circ_0002062 promotes the proliferation of pulmonary artery smooth muscle cells by regulating the Hsa-miR-942-5p/CDK6 signaling pathway

Y Wang, X Tan, Y Wu, S Cao, Y Lou, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Currently, new strategies for the diagnosis and treatment of hypoxia-induced pulmonary
hypertension (HPH) are urgently required. The unique features of circRNAs have unveiled a …

Oncogenic miR‐1825 promotes head and neck carcinogenesis via targeting FREM1

O Capik, B Gundogdu, A Tatar, A Sahin… - Journal of Cellular …, 2023 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignant
cancer type worldwide. Although the therapeutic modalities currently used for patients with …

Role of salivary miRNAs as noninvasive biomarkers in head and neck squamous cell carcinomas and oral potentially malignant disorders–reply

L Zhu, M Li, G Tang, L Shi, W Liu - Oral Oncology, 2022 - Elsevier
MicroRNAs (miRNAs) have a crucial role in the epigenetic regulation of cellular biological
processes of head and neck squamous cell carcinomas (HNSCC) including oral squamous …

Assessment of microRNA (miR)-365 effects on oral squamous carcinoma cell line phenotypes

J Coon, K Kingsley - Biomolecules, 2021 - mdpi.com
miR-365 is a microRNA that regulates transcription and has been demonstrated to promote
oncogenesis and metastasis in some cancers while suppressing these effects in others …

Osteogenic and adipogenic differentiation potential of oral cancer stem cells may offer new treatment modalities

M Jaksic Karisik, M Lazarevic, D Mitic, N Nikolic… - International Journal of …, 2023 - mdpi.com
(1) Treatment failure of oral squamous cell carcinoma (OSCC) is generally due to the
development of therapeutic resistance caused by the existence of cancer stem cells (CSCs) …

[HTML][HTML] Gastric adenocarcinoma predictive long intergenic noncoding RNA (GAPLINC) promotes oral cancer stemness by acting as a molecular sponge of miR331 …

KY Liang, NY Su, HP Yang, PL Hsieh, CY Fang… - Journal of Dental …, 2024 - Elsevier
Background/purpose Accumulating evidence has suggested that treatment failure of cancer
therapy can be attributed to cancer stem cells (CSCs). Among numerous regulators of …

Explore Novel Biomarkers and Associated Key Pathways to Perform as Potential Prognostic Biomarkers and Therapeutic Targets in Oral Cancer

F Akhter, FH Al Kahtani, ZM Sambawa, DA Alhassan… - 2022 - preprints.org
Background: Oral cancer (OC) is serious health concerning issue that has a high fatality rate.
The oral cavity has seven kinds of OC, including the lip, tongue, and floor of the mouth, as …