A numerical framework for genetic hitchhiking in populations of variable size
E Friedlander, M Steinrücken - Genetics, 2022 - academic.oup.com
Natural selection on beneficial or deleterious alleles results in an increase or decrease,
respectively, of their frequency within the population. Due to chromosomal linkage, the …
respectively, of their frequency within the population. Due to chromosomal linkage, the …
Detecting and quantifying natural selection at two linked loci from time series data of allele frequencies with forward-in-time simulations
Recent advances in DNA sequencing techniques have made it possible to monitor genomes
in great detail over time. This improvement provides an opportunity for us to study natural …
in great detail over time. This improvement provides an opportunity for us to study natural …
Estimating temporally variable selection intensity from ancient DNA data with the flexibility of modelling linkage and epistasis
Innovations in ancient DNA (aDNA) preparation and sequencing technologies have
exponentially increased the quality and quantity of aDNA data extracted from ancient …
exponentially increased the quality and quantity of aDNA data extracted from ancient …
Inferring the timing and strength of natural selection and gene migration in the evolution of chicken from ancient DNA data
W Lyu, X Dai, M Beaumont, F Yu… - Molecular Ecology …, 2022 - Wiley Online Library
With the rapid growth of the number of sequenced ancient genomes, there has been
increasing interest in using this new information to study past and present adaptation. Such …
increasing interest in using this new information to study past and present adaptation. Such …
Moment-based approximations for the Wright-Fisher model of population dynamics under natural selection at two linked loci
Z He, W Lyu, M Beaumont, F Yu - bioRxiv, 2021 - biorxiv.org
Properly modelling genetic recombination and local linkage has been shown to bring a
significant improvement to the inference of natural selection from time series genetic data …
significant improvement to the inference of natural selection from time series genetic data …
An MCMC-based method for Bayesian inference of natural selection from time series DNA data across linked loci
The rapid improvement of DNA sequencing technology has made it possible to monitor
genomes in great detail over time, which presents an opportunity for investigating natural …
genomes in great detail over time, which presents an opportunity for investigating natural …