The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

The research on advanced functional polymers is being driven by the fast-growing demand
for new functional materials that can be used in revolutionary technologies. Polymers can be …

Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Gene therapy provides a promising strategy for curing monogenetic disorders and complex
diseases. However, there are challenges associated with the use of viral delivery vectors …

Efficacy and safety of chemotherapeutic drugs constitute two major criteria in tumor
chemotherapy. Nanomedicines with tumor‐targeted properties hold great promise for …

Polymeric carriers have emerged as major non-viral alternatives for gene delivery due to
their lower immunogenicity and pathogenicity. However, during intracellular delivery of …

Drug delivery systems (DDSs) are of paramount importance to deliver drugs at the intended
targets, eg, tumor cells or tissue by prolonging blood circulation and optimizing the …

The assembly of low molecular weight polymers into highly efficient and nontoxic
nanostructures has broad applicability in gene delivery. In this study, we reported the …

Despite successful demonstration of linear polyethyleneimine (lPEI) as an effective carrier
for a wide range of gene medicine, including DNA plasmids, small interfering RNAs …

Nutrient avidity is one of the most distinctive features of tumours. However, nutrient
deprivation has yielded limited clinical benefits. In Gaucher disease, an inherited metabolic …