Investigating the postprandial metabolome after challenge tests to assess metabolic flexibility and dysregulations associated with cardiometabolic diseases

G Lépine, M Tremblay-Franco, S Bouder, L Dimina… - Nutrients, 2022 - mdpi.com
This review focuses on the added value provided by a research strategy applying
metabolomics analyses to assess phenotypic flexibility in response to different nutritional …

The relationship between the leptin/ghrelin ratio and meals with various macronutrient contents in men with different nutritional status: A randomized crossover study

E Adamska-Patruno, L Ostrowska, J Goscik… - Nutrition journal, 2018 - Springer
Background Hormones, which influence satiety and hunger, play a significant role in body
energy balance regulation. Ghrelin is a peptide that plays an important role in short-term …

Effect of TCF7L2 on the relationship between lifestyle factors and glycemic parameters: a systematic review

S Hosseinpour-Niazi, P Mirmiran, S Hosseini… - Nutrition Journal, 2022 - Springer
Background Among candidate genes related to type 2 diabetes (T2DM), one of the strongest
genes is Transcription factor 7 like 2 (TCF7L2), regarding the Genome-Wide Association …

The MC4R genetic variants are associated with lower visceral fat accumulation and higher postprandial relative increase in carbohydrate utilization in humans

E Adamska-Patruno, J Goscik, P Czajkowski… - European journal of …, 2019 - Springer
Purpose The interactions between lifestyle and genetic factors play an important role in
obesity development. Mutations in melanocortin-4-receptor (MC4R) gene are one of the …

The role of muscle decline in type 2 diabetes development: a 5-year prospective observational cohort study

K Maliszewska, E Adamska-Patruno, J Goscik… - Nutrients, 2019 - mdpi.com
The major risk factors of T2DM (type 2 diabetes mellitus) development are still under
investigation. We evaluate the possible risk factors associated with type 2 diabetes (T2DM) …

Oxidized glycerophosphatidylcholines in diabetes through non-targeted metabolomics: their annotation and biological meaning

J Godzien, B Kalaska, E Adamska-Patruno… - … of Chromatography B, 2019 - Elsevier
Lipid oxidation is one of the most important processes occurring in living cells and has been
investigated through stable end-products. Currently, new insights into many physiological …

Dietary macronutrient intake may influence the effects of TCF7L2 rs7901695 genetic variants on glucose homeostasis and obesity-related parameters: A cross …

W Bauer, E Adamska-Patruno, U Krasowska, M Moroz… - Nutrients, 2021 - mdpi.com
Transcription factor-7–like 2 (TCF7L2) is one of the most important susceptibility genes for
type 2 diabetes mellitus (T2DM). The aim of our cross-sectional population-based study was …

Evaluation of energy expenditure and oxidation of energy substrates in adult males after intake of meals with varying fat and carbohydrate content

E Adamska-Patruno, L Ostrowska, A Golonko… - Nutrients, 2018 - mdpi.com
Obesity is a result of positive energy balance. The aim of this study was to measure (in
crossover trials) the energy expenditure and oxidation of glucose and lipids, both at the …

Evaluation of transcriptomic regulations behind metabolic syndrome in obese and lean subjects

M Paczkowska-Abdulsalam, M Niemira… - International journal of …, 2020 - mdpi.com
Multiple mechanisms have been suggested to confer to the pathophysiology of metabolic
syndrome (MetS), however despite great interest from the scientific community, the exact …

An Association between Diet and MC4R Genetic Polymorphism, in Relation to Obesity and Metabolic Parameters—A Cross Sectional Population-Based Study

E Adamska-Patruno, W Bauer, D Bielska… - International Journal of …, 2021 - mdpi.com
The melanocortin-4 receptor (MC4R) gene harbours one of the strongest susceptibility loci
for obesity and obesity-related metabolic consequences. We analysed whether dietary …