The immune response to COVID-19 infection is variable. How COVID-19 influences clinical
outcomes in hospitalized patients needs to be understood through readily obtainable …

T cell-based immunotherapies including genetically engineered T cells, adoptive transfer of
tumor-infiltrating lymphocytes, and immune checkpoint blockade highlight the impressive …

Severe combined immunodeficiency (SCID) has a diverse genetic aetiology, where a
clinical phenotype, caused by single and/or multiple gene variants, can give rise to multiple …

Background: Cervical squamous cell carcinoma (CESC) is one of the most frequent
malignancies in women worldwide. The level of immune cell infiltration and immune-related …

Background Hepatocellular carcinoma (HCC) is often caused by chronic liver infection or
inflammation. Searching for potential immunotherapy targets will aid the early diagnosis and …

Background: Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive subtype of
peripheral T-cell lymphoma (PTCL) that has a poor 5-year overall survival rate due to its lack …

Severe combined immunodeficiency (SCID) is fatal if not treated with immune reconstitution.
In Egypt, T-B+ SCID accounts for 38· 5% of SCID diagnoses. An accurate genetic diagnosis …

Quantitative molecular diagnostic methods can effectively detect pathogen-specific nucleic
acid sequences, but costs associated with multi-pathogen panels hinder their widespread …

To the Editor: T cell receptor (TCR) complex consists of αβ or γδ TCR chains in combination
with four CD3 subunits, CD3ε, CD3γ, CD3δ, and CDζ [1]. This complex is required for …

To the Editor, Severe combined immunodeficiency (SCID) is the most severe form of primary
immunodeficiencies (PIDs) caused by gene variants that lead to a failure of functional T cell …