Abstract Polycyclic Aromatic Hydrocarbons (PAHs) profoundly impact public and
environmental health. Gaining a comprehensive understanding of their intricate functions …

This paper summarizes current challenges, the potential use of novel scientific
methodologies, and ways forward in the risk assessment and risk management of mixtures …

This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …

Sustainable agriculture requires balancing crop yields with the effects of pesticides on non-
target organisms, such as bees and other crop pollinators. Field studies demonstrated that …

The number of anthropogenic chemicals, manufactured, by-products, metabolites and
abiotically formed transformation products, counts to hundreds of thousands, at present …

The chemical pollution crisis severely threatens human and environmental health globally.
To tackle this challenge the establishment of an overarching international science–policy …

Abstract The EU Directive 2010/63/EU on the protection of animals used for scientific
purposes and other EU regulations, such as REACH and the Cosmetic Products Regulation …

Since the 1970s, glyphosate has become the most used herbicide of the world. The general
population is ubiquitously exposed to glyphosate. Its long-term toxicity, carcinogenic …

Agrochemicals can adversely affect biodiversity, environment and human health, and
commonly occur in mixtures with poorly characterized toxic mechanisms and health …

Human populations are chronically exposed to mixtures of toxic chemicals. Predicting the
health effects of these mixtures require a large amount of information on the mode of action …