Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …

Tramadol (TRA) causes neurotoxicity whereas trimetazidine (TMZ) is neuroprotective. The
potential involvement of the PI3K/Akt/mTOR signaling pathway in the neuroprotection of TMZ …

Endothelial dysfunction is a hallmark of cardiovascular diseases, contributing to impaired
vasodilation, altered hemodynamics, and atherosclerosis progression. Trimetazidine …

Background: Pulmonary artery hypertension (PAH) is a chronic and progressive disease.
Although current therapy has improved the disease prognosis, PAH has a poor survival rate …

This study was intended to explore the effect of proanthocyanidin (PC) combined with
trimetazidine in non‐small‐cell lung cancer (NSCLC) with radiation‐induced heart damage …

Background and Objectives: Given the fact that galectin-3 has a predictive significance on
the development of myocardial dysfunction after acute myocardial infarction, the aim of our …

Purpose: To evaluate the effect of trimetazidine on ventricular remodeling and serum levels
of cystatin C and endothelin-1 in patients with chronic heart failure (CHF). Methods: A total of …

Ischemic heart disease also referred to as coronary artery disease (CAD) is a leading cause
of death worldwide. The primary pathological mechanism underlying CAD is …

We aim to evaluate the effects of trimetazidine combined with levocarnitine on ischemic
cardiomyopathy and serum levels of cardiac troponin I (cTnI) and homocysteine (Hcy). A …

One of the possible factors in the occurrence of coronary heart disease with myocardial
infarction is oxidative stress. Oxidative stress intensifies the formation of free radicals …