[HTML][HTML] Recent Advances and Current Challenges in Stereotactic Body Radiotherapy for Ultra-Central Lung Tumors

V Salvestrini, A Lastrucci, M Banini, M Loi… - …, 2024 - pmc.ncbi.nlm.nih.gov
Stereotactic body radiotherapy has been established as a viable treatment option for
inoperable early-stage non-small cell lung cancer or secondary lesions mainly in …

[HTML][HTML] Palliative Thoracic Radiotherapy in the Era of Modern Cancer Care for NSCLC

L Kępka - Cancers, 2024 - mdpi.com
Simple Summary Radiotherapy is recognized as an effective tool for palliating symptoms
associated with loco-regional growth of NSCLC. Most evidence regarding the use of …

Structure-specific rigid dose accumulation dosimetric analysis of ablative stereotactic MRI-guided adaptive radiation therapy in ultracentral lung lesions

JM Bryant, RJ Cruz-Chamorro, A Gan… - Communications …, 2024 - nature.com
Background Definitive local therapy with stereotactic ablative radiation therapy (SABR) for
ultracentral lung lesions is associated with a high risk of toxicity, including treatment related …

Fraction Dose Escalation of Hypofractionated Radiotherapy with Concurrent Chemotherapy and Subsequent Consolidation Immunotherapy in Locally Advanced Non …

R Zhou, FJ Liu, HM Zhang, DQ Wang, PX Zhang… - Clinical Cancer …, 2024 - AACR
Purpose: This phase I trial aimed to determine the maximum tolerated fraction dose (MTFD)
of hypofractionated radiotherapy (hypo-RT) combined with concurrent chemotherapy and …

Widening the therapeutic window for central and ultra-central thoracic oligometastatic disease with stereotactic MR-guided adaptive radiation therapy (SMART)

G Lee, Z Han, E Huynh, MC Tjong, DN Cagney… - Radiotherapy and …, 2024 - Elsevier
Abstract Background/Purpose Central/ultra-central thoracic tumors are challenging to treat
with stereotactic radiotherapy due potential high-grade toxicity. Stereotactic MR-guided …

Balancing tumour control probability and toxicity in SBRT of ultra-central lung tumours–One step forward

K Lindberg - Lung Cancer, 2023 - lungcancerjournal.info
Stereotactic body radiation therapy (SBRT) of centrally located lung tumours is challenging,
given the risk of high-grade toxic effects for patients with a short tumour-bronchial distance …

[HTML][HTML] Artificial intelligence-assisted quantitative CT analysis of airway changes following SABR for central lung tumors

H Tekatli, O Bohoudi, N Hardcastle, MA Palacios… - Radiotherapy and …, 2024 - Elsevier
Introduction Use of stereotactic ablative radiotherapy (SABR) for central lung tumors can
result in up to a 35% incidence of late pulmonary toxicity. We evaluated an automated …

Dose-volume predictors of radiation pneumonitis after thoracic hypofractionated radiation therapy

A Sasse, P Oh, N Saeed, DX Yang, TJ Hayman… - Practical Radiation …, 2024 - Elsevier
Purpose Hypofractionated radiation therapy (HFRT) is a common treatment for thoracic
tumors, typically delivered as 60 Gy in 15 fractions. We aimed to identify dosimetric risk …

And Yet It Moves: Clinical Outcomes and Motion Management in Stereotactic Body Radiation Therapy (SBRT) of Centrally Located Non-Small Cell Lung Cancer …

FNOJ Habermann, D Schmitt, T Failing, DA Ziegler… - Cancers, 2024 - mdpi.com
Simple Summary We studied clinical aspects in central vs. peripheral tumors (n= 78
patients) and applied the internal organ at risk volume (IRV) concept (n= 35 patients) in …

[HTML][HTML] How to protect the proximal bronchial tree during stereotactic radiotherapy of ultracentral lung tumors: Lessons from MR-guided treatment

S Regnery, E Katsigiannopulos, H Lau… - Clinical and …, 2025 - Elsevier
Purpose To use imaging data from stereotactic MR-guided online adaptive radiotherapy
(SMART) of ultracentral lung tumors (ULT) for development of a safe non-adaptive approach …