Phase separation in membrane biology: the interplay between membrane-bound organelles and membraneless condensates
YG Zhao, H Zhang - Developmental Cell, 2020 - cell.com
In eukaryotic cells, various membrane-bound organelles compartmentalize diverse cellular
activities in a spatially and temporally controlled manner. Numerous membraneless …
activities in a spatially and temporally controlled manner. Numerous membraneless …
[HTML][HTML] The control centers of biomolecular phase separation: how membrane surfaces, PTMs, and active processes regulate condensation
WT Snead, AS Gladfelter - Molecular cell, 2019 - cell.com
Biomolecular condensation is emerging as an essential process for cellular
compartmentalization. The formation of biomolecular condensates can be driven by liquid …
compartmentalization. The formation of biomolecular condensates can be driven by liquid …
DYRK3 enables secretory trafficking by maintaining the liquid-like state of ER exit sites
The dual-specificity kinase DYRK3 controls the formation and dissolution of multiple
biomolecular condensates, regulating processes including stress recovery and mitotic …
biomolecular condensates, regulating processes including stress recovery and mitotic …
Fluorescent dyes with large Stokes shifts for super-resolution optical microscopy of biological objects: a review
The review deals with commercially available organic dyes possessing large Stokes shifts
and their applications as fluorescent labels in optical microscopy based on stimulated …
and their applications as fluorescent labels in optical microscopy based on stimulated …
COPII‐mediated trafficking at the ER/ERGIC interface
J Peotter, W Kasberg, I Pustova, A Audhya - Traffic, 2019 - Wiley Online Library
Coat proteins play multiple roles in the life cycle of a membrane‐bound transport
intermediate, functioning in lipid bilayer remodeling, cargo selection and targeting to an …
intermediate, functioning in lipid bilayer remodeling, cargo selection and targeting to an …
Wnt/β‐catenin signaling: Structure, assembly and endocytosis of the signalosome
Wnt/β‐catenin signaling is an ancient pathway that regulates key aspects of embryonic
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …
TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes
I Raote, M Ortega-Bellido, AJM Santos, O Foresti… - Elife, 2018 - elifesciences.org
Collagen export from the endoplasmic reticulum (ER) requires TANGO1, COPII coats, and
retrograde fusion of ERGIC membranes. How do these components come together to …
retrograde fusion of ERGIC membranes. How do these components come together to …
ALK fusion partners impact response to ALK inhibition: differential effects on sensitivity, cellular phenotypes, and biochemical properties
MA Childress, SM Himmelberg, H Chen, W Deng… - Molecular Cancer …, 2018 - AACR
Oncogenic tyrosine kinase fusions involving the anaplastic lymphoma kinase (ALK) are
detected in numerous tumor types. Although more than 30 distinct 5′ fusion partner genes …
detected in numerous tumor types. Although more than 30 distinct 5′ fusion partner genes …
Sorting and export of proteins at the endoplasmic reticulum
Secretory proteins are transported from the endoplasmic reticulum (ER) to the Golgi complex
in carriers that are formed by the concerted activities of cytoplasmic proteins in the coat …
in carriers that are formed by the concerted activities of cytoplasmic proteins in the coat …
A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis
Under stress, the endomembrane system undergoes reorganization to support
autophagosome biogenesis, which is a central step in autophagy. How the endomembrane …
autophagosome biogenesis, which is a central step in autophagy. How the endomembrane …