Aminotransferases (ATs) are pyridoxal 5′-phosphate–dependent enzymes that catalyze
the transamination reactions between amino acid donor and keto acid acceptor substrates …

Chiral amines are important components of 40–45% of small molecule pharmaceuticals and
many other industrially important fine chemicals and agrochemicals. Recent advances in …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

The synthesis of alcohols from amine starting materials is an excellent yet challenging
strategy for the preparation of pharmaceuticals and polymers. Here we developed a …

It is a great challenge to develop cost-effective and stable oxygen evolution reaction (OER)
electrocatalysts for energy sustainability. Herein, we report nanocomposites of rock salt type …

Transaminases are attractive catalysts for the production of enantiopure amines. However,
the poor stability of these enzymes often limits their application in biocatalysis. Here, we …

Chiral amines are essential building blocks to manufacture a plethora of valuable
compounds, including active pharmaceutical ingredients (API). It is estimated that about half …

Amine transaminases (ATAs) propose an appealing alternative to transition metal catalysts
as they can provide chiral amines of high purity from pro-chiral compounds by asymmetric …

Decades of extensive research efforts by biochemists, organic chemists, and protein
engineers have led to an understanding of the basic mechanisms of essentially all known …

Biocatalytic syntheses often require unfavorable conditions, which can adversely affect
enzyme stability. Consequently, improving the stability of biocatalysts is needed, and this is …