Pathogenic variants in genes that cause dilated cardiomyopathy (DCM) and arrhythmogenic
cardiomyopathy (ACM) convey high risks for the development of heart failure through …

Significance: Perivascular adipose tissue (PVAT), which is present surrounding most blood
vessels, from the aorta to the microvasculature of the dermis, is mainly composed of fat cells …

Chronic inflammation drives the development of atherosclerosis. Despite optimal treatment
of classical cardiovascular risk factors, a substantial portion of the population has elevated …

The CD40–CD40 ligand (CD40L) dyad represents a scientific and clinical field that has
raised many controversies in the past and cannot be clearly defined as being an either …

Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …

Initially thought to only provide mechanical support for the underlying blood vessels,
perivascular adipose tissue (PVAT) has now emerged as a regulator of vascular function. A …

Epigenetic changes, particularly non‐coding RNAs, have been implicated extensively in the
pathogenesis of vascular diseases. Specific miRNAs are involved in the differentiation …

Microparticles (MPs) are the major carriers of circulating microRNAs. Our previous study has
shown that microRNA (miR)-19b in endothelial cell-derived microparticles (EMPs) is …

Heading aims Abdominal aortic aneurysm (AAA) is featured by the growth impediment and
apoptosis surge of VSMCs (vascular smooth muscle cells). MicroRNAs (miRNAs) are …

Lipid-based nanoparticles are a useful tool for nucleic acids delivery and have been
regarded as a promising approach for diverse diseases. However, off-targets effects are a …