Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …

Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Ovarian cancer is one of the most common gynecological malignancies. Upon initial
diagnosis, the majority of patients present with widespread metastatic growth within the …

A rapidly growing body of experimental evidence has begun to shed light on the wide
ranging molecular mechanisms which modulate intra-and inter-cellular communications. A …

The tumor microenvironment is replete with factors secreted and internalized by surrounding
cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that are …

Extracellular vesicles, including exosomes, are nanoscale membrane particles that carry
molecular information on parental cells. They are being pursued as biomarkers of cancers …

While there is considerable contemporary interest in elucidating the role of placenta-derived
extracellular vesicles in normal and complicated pregnancies and their utility as biomarkers …

Background Human placenta releases specific nanovesicles (ie exosomes) into the
maternal circulation during pregnancy, however, the presence of placenta-derived …

Exosomal miRNAs are proposed as excellent candidate biomarkers for clinical applications.
However, little is known about their potential roles as prognostic biomarkers in lung cancer …