Proper chromosome segregation is crucial for cell division. In eukaryotes, this is achieved by
the kinetochore, an evolutionarily conserved multiprotein complex that physically links the …

Backgrounds Chemotherapy is a standard systemic treatment option for triple-negative
breast cancer (TNBC). Cisplatin has been used to treat TNBC, but frequently leads to …

There has been a great deal of research on cell division and its mechanisms; however, its
processes still have many unknowns. To find novel proteins that regulate cell division, we …

Astrin, which is a spindle-associated protein, was found to be closely related to mitotic
spindle formation and maintenance. It interacts with other spindle-related proteins to play a …

Endometrial hyperplasia (EH) is a precursor for endometrial cancer (EC). However,
biomarkers for the progression from EH to EC and standard prognostic biomarkers for EC …

Objective: Spindle pole body component 25 (SPC25) is an important cyclin involved in
chromosome segregation and spindle dynamics regulation during mitosis. However, the role …

Introduction Glioma is the most frequent and lethal form of primary brain tumor. The
molecular mechanism of oncogenesis and progression of glioma still remains unclear …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors globally and
often develops on the foundation of chronic liver disease or cirrhosis. Cirrhosis is a clinically …

Abstract Development of resistance against most of the clinical antibiotics is a menace to
mankind for their use in future. Present study aimed at design and synthesis of some …

目的应用生物信息学技术构建草酸钙肾结石大鼠miRNA-mRNA 调控网络并筛选出调控草酸钙
肾结石形成的关键分子. 方法从基因表达汇编(GEO) 数据库中筛选出乙二醇喂养14 d …