Nephrotic syndrome is defined by nephrotic-range proteinuria (≥ 40 mg/m2/hour or urine
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …

Nephrotic syndrome is a common glomerular disease in children with significant variability
in both incidence and steroid responsiveness among various ethnic groups. The average …

Results Over 10 years, the overall incidence increased from 1.99/100,000 to 4.71/100,000
among children ages 1–18 years old. In 2011, South Asians had a higher incidence rate …

Background Information about renal diseases in children is available from national registries
of renal biopsies. Aim of the study was to compare the clinical presentation of glomerular …

Background Reports on the histopathology of childhood nephrotic syndrome (NS) had
emanated from our Centre since the 1960s and by the late 1980s and early 1990s, a change …

Prevalence, clinicopathological features, and outcome of childhood idiopathic steroid-
resistant nephrotic syndrome (ISRNS) vary in different countries. We report on these …

Background The role of the multidrug resistance-1 (MDR1 or ABCB1) gene polymorphisms
1236T> C, 2677T> G, and 3435T> C was studied in relation to susceptibility, demographics …

Objective: To compare the efficacy of tacrolimus versus cyclosporine (Calcineurin Inhibitors)
in the management of childhood steroid-resistant nephritic syndrome (SRNS). Study Design …

Renal biopsy is an important tool for the diagnosis of acute and chronic glomerular diseases
in children. We aimed to analyze the spectrum of clinical indications and histopathological …

Mutations in the NPHS1, NPHS2, LAMB2, and the WT1 genes are responsible for causing
nephrotic syndrome (NS) in two third of the early onset cases. This study was carried out to …