The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …
Alternatives to traditional categorical diagnoses have been proposed to improve the validity and utility of psychiatric nosology. This paper continues the companion review of an …
Early socioeconomic status (SES) has consistently been associated with child health and cognitive outcomes, in addition to alterations in brain function and connectivity. The goal of …
Importance Childhood psychoticlike experiences (PLEs) are associated with greater odds of a diagnosis of a psychotic disorder during adulthood. However, no known, well-validated …
NR Karcher, KJ O'Brien, S Kandala, DM Barch - Biological psychiatry, 2019 - Elsevier
Abstract Background Psychotic-like experiences (PLEs) during childhood are associated with greater risk of developing a psychotic disorder (and other mental disorders) …
JM Sheffield, S Kandala, CA Tamminga… - JAMA …, 2017 - jamanetwork.com
Importance Cognitive impairment occurs across the psychosis spectrum and is associated with functional outcome. However, it is unknown whether these shared manifestations of …
Importance Previous research indicates that cannabis use is associated with psychotic-like experiences (PLEs). However, it is unclear whether this association results from …
Background Psychotic symptoms are proposed to lie on a continuum, ranging from isolated psychosis-like experiences (PLEs) in nonclinical populations to frank disorder. Here, we …
J Miyata - Neurobiology of disease, 2019 - Elsevier
Attribution of abnormally heightened salience to daily-life stimuli is considered to underlie psychosis. Dopaminergic hyperactivity in the midbrain-striatum is thought to cause such …