Oral epithelial dysplasia: recognition, grading and clinical significance

E Odell, O Kujan, S Warnakulasuriya, P Sloan - Oral Diseases, 2021 - Wiley Online Library
Histopathological grading of epithelial dysplasia remains the principal laboratory method for
assessing the risk of malignant transformation in oral potentially malignant disorders …

Management of oral potentially malignant disorders

AR Kerr, G Lodi - Oral Diseases, 2021 - Wiley Online Library
Patients with oral potentially malignant disorders (OPMDs), including oral leukoplakia and
erythroplakia, proliferative verrucous leukoplakia, oral submucous fibrosis, and oral lichen …

TDO2+ myofibroblasts mediate immune suppression in malignant transformation of squamous cell carcinoma

S Hu, H Lu, W Xie, D Wang, Z Shan… - The Journal of …, 2022 - Am Soc Clin Investig
Characterization of the dynamic change in the immunological landscape during malignant
transformation from precancerous lesions to cancerous lesions in squamous cell carcinoma …

The global prevalence of oral leukoplakia: a systematic review and meta-analysis from 1996 to 2022

C Zhang, B Li, X Zeng, XS Hu, H Hua - BMC Oral Health, 2023 - Springer
Background Oral leukoplakia (OLK) is a common oral potentially malignant disorder. The
global prevalence of solely OLK was published in 2003, while the prevalence varied among …

Elucidating the genetic landscape of oral leukoplakia to predict malignant transformation

LJ Wils, JB Poell, A Brink, I Evren, ER Brouns… - Clinical Cancer …, 2023 - AACR
Purpose: Oral leukoplakia is the most common oral potentially malignant disorder with an
annual malignant transformation rate of 1% to 5%. Consequently, oral leukoplakia patients …

Development and validation of a nomogram prediction model for malignant transformation of oral potentially malignant disorders

X Cai, J Zhang, Y Han, Q Tang, H Zhang, T Li - Oral Oncology, 2021 - Elsevier
Objective Oral potentially malignant disorders have increased the risk of oral squamous cell
carcinoma. This study developed a nomogram model to assess the risks of malignant …

Resection margins in head and neck cancer surgery: an update of residual disease and field cancerization

AS Pierik, CR Leemans, RH Brakenhoff - Cancers, 2021 - mdpi.com
Simple Summary Curative treatment of head and neck squamous cell carcinoma (HNSCC)
is largely dependent on locoregional control of the disease. However, HNSCCs frequently …

[HTML][HTML] Regular clinical follow-up of oral potentially malignant disorders results in improved survival for patients who develop oral cancer

F Jäwert, J Nyman, E Olsson, C Adok, M Helmersson… - Oral oncology, 2021 - Elsevier
Objectives To evaluate whether clinical follow-up programs of oral potentially malignant
disorders (OPMD) result in earlier detection and improved survival rates if malignant …

Malignant transformation rate of oral leukoplakia in the past 20 years: A systematic review and meta‐analysis

JY Guan, YH Luo, YY Lin, ZY Wu, JY Ye… - Journal of Oral …, 2023 - Wiley Online Library
Background This meta‐analysis aimed to assess the rate of malignant transformation (MT) of
oral leukoplakia (OL) and to study potential risk factors for the MT of OL into oral squamous …

Oral cancer and oral potentially malignant disorders in patients with Fanconi anemia–A systematic review

NCM Santana, ACVP de Sena, PA da Silva Rocha… - Oral Oncology, 2024 - Elsevier
The purpose of the present study was to perform a systematic review focusing on oral
squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) in …