Exploring the role of Locus Coeruleus in Alzheimer's Disease: a Comprehensive Update on MRI studies and implications

A Galgani, FS Giorgi - Current Neurology and Neuroscience Reports, 2023 - Springer
Abstract Purpose of Review Performing a thorough review of magnetic resonance imaging
(MRI) studies assessing locus coeruleus (LC) integrity in ageing and Alzheimer's disease …

[HTML][HTML] The Locus Coeruleus–Noradrenaline system: Looking into Alzheimer's therapeutics with rose coloured glasses

T Behl, I Kaur, A Sehgal, S Singh, HA Makeen… - Biomedicine & …, 2022 - Elsevier
Owing to the challenging ethos of global healthcare system, the Alzheimer's Disease (AD)
researchers are consistently striving for a suitable target for disease amelioration. Besides …

New approaches for the quantification and targeting of noradrenergic dysfunction in Alzheimer's disease

M David, PA Malhotra - Annals of Clinical and Translational …, 2022 - Wiley Online Library
There is clear, early noradrenergic dysfunction in Alzheimer's disease. This is likely
secondary to pathological tau deposition in the locus coeruleus, the pontine nucleus that …

Physical activity status prevents symptoms of long covid: Sulcovid-19 survey

JQS Rocha, EL Caputo, YP Vieira, MS Afonso… - BMC Sports Science …, 2023 - Springer
Background Physical activity is indicated as a treatment for Long COVID, but prevention is
unknown. This study aimed to investigate the relationship between physical activity (PA) …

[HTML][HTML] Slower speed of blood pressure recovery after standing is associated with accelerated brain ageing: Evidence from The Irish Longitudinal Study on Ageing …

MA Shirsath, JD O'Connor, R Boyle, L Newman… - … circulation-cognition and …, 2024 - Elsevier
Background Impaired recovery of blood pressure (BP) in response to standing up is a
prevalent condition in older individuals. We evaluated the relationship between the early …

Noradrenaline in Alzheimer's Disease: A New Potential Therapeutic Target

JL Muñoz Madrigal, I López Gutiérrez, C Dello Russo… - 2022 - docta.ucm.es
A growing body of evidence demonstrates the important role of the noradrenergic system in
the pathogenesis of many neurodegenerative processes, especially Alzheimer's disease …