Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …

Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes are critical for maintaining the homeostasis of the CNS. Increasing evidence
suggests that a number of neurological and neuropsychiatric disorders, including chronic …

The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …

Astrocytes are highly complex cells with many emerging putative roles in brain function. Of
these, gliotransmission (active information transfer from glia to neurons) has probably the …

When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …

The role of astrocytes in neuronal function has received increasing recognition, but
disagreement remains about their function at the circuit level. Here we use in vivo two …

Synaptic dysfunction is a hallmark of many neurodegenerative and psychiatric brain
disorders, yet we know little about the mechanisms that underlie synaptic vulnerability …

Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex
of Alzheimer's disease (AD) patients several decades ago. However, their role in AD …

Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …