The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Obesity is an important aspect of the metabolic syndrome and is often associated with
chronic inflammation. In this context, inflammation of organs participating in energy …

In mammalian cells, elongases and desaturases play critical roles in regulating the length
and degree of unsaturation of fatty acids and thereby their functions and metabolic fates. In …

Atherosclerosis (AS) is a major cause of cardiovascular diseases such as coronary heart
disease, heart failure and stroke. Abnormal lipid metabolism, oxidative stress and …

Clinical interest in de novo lipogenesis has been sparked by recent studies in rodents
demonstrating that de novo lipogenesis specifically in white adipose tissue produces the …

ABSTRACT Stearoyl CoA desaturase 1 (SCD1) catalyzes the rate-limiting step in the
production of MUFA that are major components of tissue lipids. Alteration in SCD1 …

Stearoyl‐CoA desaturase 1 (SCD1) is an essential lipogenic enzyme that has been shown
to play an intrinsic role in the development of obesity and related conditions, such as insulin …

Different lipid fractions in humans have characteristic fatty acid profiles and these are
maintained partly through diet and to a lesser extent through endogenous synthesis. The …

The gut microbiota plays a key role in host metabolism. Toll-like receptor 5 (TLR5), a
flagellin receptor, is required for gut microbiota homeostasis. Accordingly, TLR5-deficient …

The interaction between fat deposition and inflammation during obesity contributes to the
development of non-alcoholic fatty liver disease (NAFLD). The present study examined the …