Neutrophil extracellular traps and their implications in cardiovascular and inflammatory disease

J Klopf, C Brostjan, W Eilenberg… - International journal of …, 2021 - mdpi.com
Neutrophils are primary effector cells of innate immunity and fight infection by phagocytosis
and degranulation. Activated neutrophils also release neutrophil extracellular traps (NETs) …

Multiple roles for neutrophils in atherosclerosis

O Soehnlein - Circulation research, 2012 - Am Heart Assoc
Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis

M Drechsler, RTA Megens, M van Zandvoort, C Weber… - Circulation, 2010 - Am Heart Assoc
Background—Inflammation and activation of immune cells are key mechanisms in the
development of atherosclerosis. Previous data indicate important roles for monocytes and T …

Inflammation in peripheral artery disease

G Brevetti, G Giugliano, L Brevetti, WR Hiatt - Circulation, 2010 - Am Heart Assoc
Peripheral artery disease (PAD), which consists of partial or complete obstruction of the
arteries in the lower limbs, is one of the most common manifestations of atherosclerosis …

Increased burden of inflammation over time is associated with the extent of atherosclerotic plaques in patients with psoriatic arthritis

L Eder, A Thavaneswaran, V Chandran… - Annals of the …, 2015 - ard.bmj.com
Aim To investigate whether a higher burden of inflammation is associated with more severe
atherosclerosis in patients with psoriatic arthritis (PsA). Methods Patients from a large PsA …

Association between neutrophil‐lymphocyte and platelet‐lymphocyte ratios and coronary artery calcification score among asymptomatic patients: data from a cross …

CV Serrano Jr, FR De Mattos, FG Pitta… - Mediators of …, 2019 - Wiley Online Library
Introduction. Atherosclerosis is a low‐grade inflammatory disease. Among markers of
inflammation, importance has been given to the neutrophil‐lymphocyte ratio (NLR) and …

Platelet-to-lymphocyte ratio relates to poor prognosis in elderly patients with acute myocardial infarction

L Li, Y Ma, X Geng, Z Tan, J Wang, C Cui… - Aging clinical and …, 2021 - Springer
Background The platelet to lymphocyte ratio (PLR) is a novel biomarker to predict the
prognosis of acute myocardial infarction (AMI) patients. Aim The study aimed to evaluate the …

Rutin and curcumin reduce inflammation, triglyceride levels and ADA activity in serum and immune cells in a model of hyperlipidemia

AG Manzoni, DF Passos, JLG da Silva… - Blood Cells, Molecules …, 2019 - Elsevier
Hyperlipidemia is associated with endothelial dysfunction and inflammatory disorders.
Adenosine and adenosine deaminase (ADA) modulate immune responses and lipid …

Interactions between dyslipidemia and the immune system and their relevance as putative therapeutic targets in atherosclerosis

M Lacy, D Atzler, R Liu, M De Winther, C Weber… - Pharmacology & …, 2019 - Elsevier
Cardiovascular disease (CVD) continues to be a leading cause of death worldwide with
atherosclerosis being the major underlying pathology. The interplay between lipids and …

Platelet‐to‐lymphocyte ratio a potential prognosticator in acute myocardial infarction: A prospective longitudinal study

H Wang, L Li, Y Ma - Clinical Cardiology, 2023 - Wiley Online Library
Background The ratio of platelets to lymphocytes (PLR) can serve as a potential biomarker
for predicting the prognosis of individuals with acute myocardial infarction (AMI). Aim The …