Animal models for COVID-19: advances, gaps and perspectives

C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - Signal transduction and …, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …

[HTML][HTML] Role of the humoral immune response during COVID-19: guilty or not guilty?

M Yaugel-Novoa, T Bourlet, S Paul - Mucosal Immunology, 2022 - Elsevier
Systemic and mucosal humoral immune responses are crucial to fight respiratory viral
infections in the current pandemic of COVID-19 caused by the SARS-CoV-2 virus. During …

Dengue and COVID-19: two sides of the same coin

GN Malavige, C Jeewandara, GS Ogg - Journal of biomedical science, 2022 - Springer
Abstract Background Many countries in Asia and Latin America are currently facing a double
burden of outbreaks due to dengue and COVID-19. Here we discuss the similarities and …

SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry

O Matveeva, Y Nechipurenko, D Lagutkin… - Frontiers in …, 2022 - frontiersin.org
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …

A review: understanding molecular mechanisms of antibody-dependent enhancement in viral infections

J Sawant, A Patil, S Kurle - Vaccines, 2023 - mdpi.com
Antibody Dependent Enhancement (ADE) of an infection has been of interest in the
investigation of many viruses. It is associated with the severity of the infection. ADE is …

[HTML][HTML] Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know

WM Zelek, RA Harrison - Immunobiology, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

Structural dynamics of the SARS-CoV-2 spike protein: A 2-year retrospective analysis of SARS-CoV-2 variants (from Alpha to Omicron) reveals an early divergence …

P Guérin, N Yahi, F Azzaz, H Chahinian, JM Sabatier… - Molecules, 2022 - mdpi.com
We analyzed the epitope evolution of the spike protein in 1,860,489 SARS-CoV-2 genomes.
The structural dynamics of these epitopes was determined by molecular modeling …

Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody

T Phan, C Zitzmann, KW Chew, DM Smith… - PLoS …, 2024 - journals.plos.org
To mitigate the loss of lives during the COVID-19 pandemic, emergency use authorization
was given to several anti-SARS-CoV-2 monoclonal antibody (mAb) therapies for the …

Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking

CF Tien, WT Tsai, CH Chen, HJ Chou, MM Zhang… - IScience, 2022 - cell.com
Summary Post-translational modifications (PTMs), such as glycosylation and palmitoylation,
are critical to protein folding, stability, intracellular trafficking, and function. Understanding …

Neutralizing and enhancing antibodies against SARS-CoV-2

Y Liu, H Arase - Inflammation and Regeneration, 2022 - Springer
The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a
huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an …