Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

Patients with mammographically dense breast tissue have a greatly increased risk of
developing breast cancer. Dense breast tissue contains more stromal collagen, which …

Tissue engineering is an interdisciplinary field that combines the knowledge and technology
of cells, engineering materials, and suitable biochemical factor to create artificial organs and …

Osteoarthritis (OA) afflicts more than 20 million people in the United States and about 10% of
adults over the age of 50 years [1]. It has been demonstrated that 2.0% of women and 1.4 …

Knee ligament injuries are common, particularly in sports and sports related activities.
Rupture of these ligaments upsets the balance between knee mobility and stability, resulting …

Tendons are able to remodel their mechanical and morphological properties in response to
mechanical loading. However, there is little information about the effects of controlled …

This paper reports the fabrication of scaffolds consisting of radially aligned poly (ε-
caprolactone) nanofibers by utilizing a collector composed of a central point electrode and a …

Engineered ligament tissues are promising materials for the repair of tears and ruptures, but
require the development of biomaterial scaffolds that not only support physiologically …