Infections as a major preventable cause of human cancer

H Kuper, HO Adami… - Journal of internal …, 2001 - Wiley Online Library
Kuper H, Adami H‐O & Trichopoulos D (Harvard School of Public Health, Boston, MA, USA;
Karolinska Institute, Stockholm, Sweden; University of Athens Medical School, Greece) …

The biogenesis and functions of lipid bodies in animals, plants and microorganisms

DJ Murphy - Progress in lipid research, 2001 - Elsevier
What are lipid bodies? One of the problems in answering this apparently simple question is
that these macromolecular proteolipid assemblies can be relatively heterogeneous with …

A meta‐analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma

F Donato, P Boffetta, M Puoti - International journal of cancer, 1998 - Wiley Online Library
The aim of the study was to assess whether co‐infection by hepatitis‐B virus (HBV) and
hepatitis‐C virus (HCV) is associated with a higher risk of developing hepatocellular …

Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets

G Barba, F Harper, T Harada… - Proceedings of the …, 1997 - National Acad Sciences
There is now abundant evidence to substantiate an important role of hepatitis C virus (HCV)
core protein in cellular gene expression as well as in the viral cycle. Thus the subcellular …

Hepatitis C virus core protein induces hepatic steatosis in transgenic mice

K Moriya, H Yotsuyanagi, Y Shintani… - Journal of general …, 1997 - microbiologyresearch.org
Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide, which finally leads
to development of hepatocellular carcinoma. Chronic hepatitis C is characterized by several …

Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties

KE Reed, CM Rice - The Hepatitis C Viruses, 2000 - Springer
Hepatitis C was first recognized as a distinct form of liver disease in the mid-1970s with the
advent of diagnostic tests for hepatitis A and B virus infection (A LTER et al. 1975; P RINCE …

Genetic mechanisms of hepatocarcinogenesis

MA Feitelson, B Sun, N Lale Satiroglu Tufan, J Liu… - Oncogene, 2002 - nature.com
The development of hepatocellular carcinoma (HCC) is a multistep process associated with
changes in host gene expression, some of which correlate with the appearance and …

Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes

McLauchlan - Journal of viral hepatitis, 2000 - Wiley Online Library
The core protein of hepatitis C virus (HCV) is believed to form the capsid shell of virus
particles. Maturation of the protein is achieved through cleavage by host cell proteases to …

The molecular virology of hepatitis C

ME Major, SM Feinstone - Hepatology, 1997 - journals.lww.com
Hepatitis C virus (HCV), first identified in 1989, 1 is the structure. 10, 20 The proposed
secondary structure20, 21 is shown major causative agent of parenterally transmitted and …

Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient

T Kato, A Furusaka, M Miyamoto, T Date… - Journal of medical …, 2001 - Wiley Online Library
Although hepatitis C virus (HCV) is a major cause of non‐A non‐B hepatitis, its pathogenic
role in fulminant hepatitis remains controversial. A 32‐year‐old man contracted hepatitis …