Finding the balance between over-and under-treatment of ductal carcinoma in situ (DCIS)

EJ Groen, LE Elshof, LL Visser, J Emiel… - The Breast, 2017 - Elsevier
With the widespread adoption of population-based breast cancer screening, ductal
carcinoma in situ (DCIS) has come to represent 20–25% of all breast neoplastic lesions …

Predictors of recurrence for ductal carcinoma in situ after breast-conserving surgery

JR Benson, GC Wishart - The Lancet Oncology, 2013 - thelancet.com
Ductal carcinoma in situ (DCIS) constitutes a major public health problem, with up to half of
screen-detected cancers representing pure forms of DCIS without evidence of invasion. A …

Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01): a randomised, factorial, multicentre, open …

BH Chua, EK Link, IH Kunkler, TJ Whelan… - The Lancet, 2022 - thelancet.com
Background Whole breast irradiation (WBI) after conservative surgery for ductal carcinoma
in situ (DCIS) reduces local recurrence. We investigated whether a tumour bed boost after …

A multigene expression assay to predict local recurrence risk for ductal carcinoma in situ of the breast

LJ Solin, R Gray, FL Baehner, SM Butler… - Journal of the …, 2013 - academic.oup.com
Background For women with ductal carcinoma in situ (DCIS) of the breast, the risk of
developing an ipsilateral breast event (IBE; defined as local recurrence of DCIS or invasive …

Cancer statistics: breast cancer in situ

EM Ward, CE DeSantis, CC Lin… - CA: a cancer journal …, 2015 - Wiley Online Library
An estimated 60,290 new cases of breast carcinoma in situ are expected to be diagnosed in
2015, and approximately 1 in 33 women is likely to receive an in situ breast cancer …

Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study

A Hennigs, F Riedel, A Gondos, P Sinn, P Schirmacher… - BMC cancer, 2016 - Springer
Abstract Background In Germany, most breast cancer patients are treated in specialized
breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate …

A Biological Signature for Breast Ductal Carcinoma In Situ to Predict Radiotherapy Benefit and Assess Recurrence Risk

T Bremer, PW Whitworth, R Patel, J Savala, T Barry… - Clinical cancer …, 2018 - AACR
Purpose: Ductal carcinoma in situ (DCIS) patients and their physicians currently face
challenging treatment decisions with limited information about the individual's subsequent …

Radiotherapy of breast cancer—professional guideline 1st Central-Eastern European professional consensus statement on breast cancer

C Polgár, Z Kahán, O Ivanov, M Chorváth… - Pathology and …, 2022 - por-journal.com
The international radiotherapy (RT) expert panel has revised and updated the RT guidelines
that were accepted in 2020 at the 4th Hungarian Breast Cancer Consensus Conference …

Pathological features of 11,337 patients with primary ductal carcinoma in situ (DCIS) and subsequent events: results from the UK Sloane Project

AM Shaaban, B Hilton, K Clements… - British journal of …, 2021 - nature.com
Abstract Background The Sloane audit compares screen-detected ductal carcinoma in situ
(DCIS) pathology with subsequent management and outcomes. Methods This was a …

Cause-specific mortality in a population-based cohort of 9799 women treated for ductal carcinoma in situ

LE Elshof, MK Schmidt, J Emiel… - Annals of …, 2018 - journals.lww.com
Objective: To assess cause-specific mortality in women treated for ductal carcinoma in situ
(DCIS). Background: From screening and treatment perspective, it is relevant to weigh the …