Orthostatic hypotension: epidemiology, prognosis, and treatment

F Ricci, R De Caterina, A Fedorowski - Journal of the American College of …, 2015 - jacc.org
Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of
underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic …

A global perspective on an emotional learning model proposal

AR Faria, A Almeida, C Martins, R Gonçalves… - Telematics and …, 2017 - Elsevier
Existing literature argues that emotions have a significant impact on the majority of human
activities and functions. The learning process is one of the activities on which emotions have …

Effects of 1α,25-Dihydroxyvitamin D3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in …

A Balla, YS Jeong, HJ Kim, YJ Lee, SJ Chung, YJ Chae… - Pharmaceutics, 2021 - mdpi.com
In this study, possible changes in the expression of rat organic cationic transporters (rOCTs)
and rat multidrug and toxin extrusion proteins (rMATEs) following treatment with 1α, 25 …

[HTML][HTML] Effect of infrared light on live blood cells: Role of β-carotene

S Barkur, A Bankapur, S Chidangil, D Mathur - Journal of Photochemistry …, 2017 - Elsevier
We have utilized Raman tweezers to measure and assign micro-Raman spectra of optically
trapped, live red blood cells (RBCs), white blood cells (WBCs) and platelets. Various types …

Finite element modeling and simulation of arteries in the human arm to study the aortic pulse wave propagation

P Choudhari, MS Panse - Procedia Computer Science, 2016 - Elsevier
Finite modelling and simulation of the arterial network in the human arm has been presented
in this paper with an objective to study the aortic pulse wave propagation. In the biomedical …

Pathways from parental educational attainment to adolescent blood pressure

MK Kwok, CM Schooling, SV Subramanian… - Journal of …, 2016 - journals.lww.com
Objectives: Lower parental education is associated with higher adolescent blood pressure
(BP). We examined the contribution of modifiable risk factors from infancy to adolescence …

Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ …

RA Dave, ME Morris - Journal of pharmacokinetics and …, 2015 - Springer
This study developed a semi-mechanistic kidney model incorporating physiologically-
relevant fluid reabsorption and transporter-mediated active reabsorption. The model was …

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and …

YS Jeong, A Balla, KH Chun, SJ Chung, HJ Maeng - Pharmaceutics, 2019 - mdpi.com
Previous observations demonstrated that cimetidine decreased the clearance of
procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) …

Effects of renal impairment on transporter‐mediated renal reabsorption of drugs and renal drug–drug interactions: A simulation‐based study

KE Follman, RA Dave, ME Morris - Biopharmaceutics & drug …, 2018 - Wiley Online Library
Renal impairment (RI) significantly impacts the clearance of drugs through changes in the
glomerular filtration rate, protein binding and alterations in the expression of renal drug …

Spacer length: A determining factor in the design of galactosyl ligands for hepatoma cell-specific liposomal gene delivery

L Mbatha, S Chakravorty, CB de Koning… - Current Drug …, 2016 - ingentaconnect.com
Background: Use of nucleic acids to treat acquired or inherited hepatic diseases has
considerable potential. Although recombinant viruses are popular vectors, interest in …