Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

I Mahar, FR Bambico, N Mechawar… - … & Biobehavioral Reviews, 2014 - Elsevier
Chronic stressful life events are risk factors for developing major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …

Understanding vulnerability for depression from a cognitive neuroscience perspective: A reappraisal of attentional factors and a new conceptual framework

R De Raedt, EHW Koster - Cognitive, Affective, & Behavioral Neuroscience, 2010 - Springer
We propose a framework to understand increases in vulnerability for depression after
recurrent episodes that links attention processes and schema activation to negative mood …

Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours

X Yu, Y Bai, B Han, M Ju, T Tang… - Journal of …, 2022 - Wiley Online Library
Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and
severely limits psychosocial function and quality of life, but no effective medication is …

Understanding nutrition, depression and mental illnesses

TSS Rao, MR Asha, BN Ramesh… - Indian journal of …, 2008 - journals.lww.com
Few people are aware of the connection between nutrition and depression while they easily
understand the connection between nutritional deficiencies and physical illness. Depression …

HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression

IH Gotlib, J Joormann, KL Minor, J Hallmayer - Biological psychiatry, 2008 - Elsevier
BACKGROUND: Recent evidence indicates that individuals who are homozygous for the
short (s) allele in the promoter region of the serotonin transporter gene have higher rates of …

Nutritional therapies for mental disorders

SE Lakhan, KF Vieira - Nutrition journal, 2008 - Springer
According to the Diagnostic and Statistical Manual of Mental Disorders, 4 out of the 10
leading causes of disability in the US and other developed countries are mental disorders …

Neurobiological mechanisms in major depressive disorder

M aan het Rot, SJ Mathew, DS Charney - Cmaj, 2009 - Can Med Assoc
Scientists have not identified a gene or a series of genes that cause depression. Rather,
certain variations in genes, called polymorphisms, may increase risk for depression. Genes …

Chemical sensing of neurotransmitters

T Pradhan, HS Jung, JH Jang, TW Kim… - Chemical Society …, 2014 - pubs.rsc.org
In the past few decades, the development of chemosensors for neurotransmitters has
emerged as a research area of significant importance, which attracted a tremendous amount …

Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters

CB Zhu, KM Lindler, AW Owens, LC Daws… - …, 2010 - nature.com
Abstract Serotonin (5-hydroxytryptamine, 5-HT) has long been implicated in regulation of
mood. Medications that block the neuronal 5-HT transporter (SERT) are used as major …

Cross brain–gut analysis highlighted hub genes and LncRNA networks differentially modified during leucine consumption and endurance exercise in mice with …

N Abedpoor, F Taghian, F Hajibabaie - Molecular Neurobiology, 2022 - Springer
Depression is a frequent mood disorder that might impair the brain-gut axis. In this study, we
divided 30 mice into five groups: untreated mice, mice with depression-like behaviors, mice …