Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
Cell Culture Based in vitro Test Systems for Anticancer Drug Screening
The development of new high-tech systems for screening anticancer drugs is one of the
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …
Biomaterial-assisted regenerative medicine
T Nii, Y Katayama - International journal of molecular sciences, 2021 - mdpi.com
This review aims to show case recent regenerative medicine based on biomaterial
technologies. Regenerative medicine has arousing substantial interest throughout the world …
technologies. Regenerative medicine has arousing substantial interest throughout the world …
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
S Ortiz-Espinosa, X Morales, Y Senent, D Alignani… - Cancer letters, 2022 - Elsevier
Myeloid-derived suppressor cells (MDSCs) play a major role in cancer progression. In this
study, we investigated the mechanisms by which complement C5a increases the capacity of …
study, we investigated the mechanisms by which complement C5a increases the capacity of …
Microfluidic lung airway-on-a-chip with arrayable suspended gels for studying epithelial and smooth muscle cell interactions
Chronic lung diseases (CLDs) are regulated by complex interactions between many
different cell types residing in lung airway tissues. Specifically, interactions between airway …
different cell types residing in lung airway tissues. Specifically, interactions between airway …
Advancement of scaffold-based 3D cellular models in cancer tissue engineering: an update
The lack of traditional cancer treatments has resulted in an increased need for new clinical
techniques. Standard two-dimensional (2D) models used to validate drug efficacy and …
techniques. Standard two-dimensional (2D) models used to validate drug efficacy and …
Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer
Platelets extravasate from the circulation into tumor microenvironment, enable metastasis,
and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor …
and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor …
[HTML][HTML] Microfluidics meets 3D cancer cell migration
An early step of metastasis requires a complex and coordinated migration of invasive tumor
cells into the surrounding tumor microenvironment (TME), which contains extracellular …
cells into the surrounding tumor microenvironment (TME), which contains extracellular …
A review of microfluidic approaches for investigating cancer extravasation during metastasis
Metastases, or migration of cancers, are common and severe cancer complications.
Although the 5-year survival rates of primary tumors have greatly improved, those of …
Although the 5-year survival rates of primary tumors have greatly improved, those of …
[HTML][HTML] Collagen for neural tissue engineering: Materials, strategies, and challenges
Neural tissue engineering (NTE) has made remarkable strides in recent years and holds
great promise for treating several devastating neurological disorders. Selecting optimal …
great promise for treating several devastating neurological disorders. Selecting optimal …