Part II of the consensus guidelines updates the recommendations for the periprocedural
management of thrombotic and bleeding risks in patients who require image-guided …

Abstract The American Society of Regional Anesthesia and Pain Medicine (ASRA) 2012
survey of meeting attendees showed that existing ASRA anticoagulation guidelines for …

Cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of more drugs in clinical use
than any other foreign compound–metabolizing enzyme in humans. Recently, increasing …

Interventional spine and pain procedures cover a far broader spectrum than those for
regional anesthesia, reflecting diverse targets and goals. When surveyed, interventional …

Palbociclib, ribociclib, and abemaciclib belong to the third generation of cyclin-dependent
kinases inhibitors (CDKis), an established therapeutic class for advanced and metastatic …

Aim: To systematically investigate the genetic polymorphisms of the CYP3A4 gene in a Han
Chinese population. Materials & methods: The promoter and exons of CYP3A4 gene in …

Methods Eight hundred thirty-four adult patients were included in this study, of whom 130
used aripiprazole, 312 used haloperidol, 86 used pimozide, and 396 used risperidone …

CYP3A enzymes participate in the elimination of ticagrelor and the bioactivation of
clopidogrel and prasugrel. We studied the effects of functional CYP3A genetic variants …

Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are the serious public
health problems worldwide. Moreover, it is estimated that MetS patients have about five-fold …

Introduction: Aspirin, clopidogrel, prasugrel and ticagrelor are antiplatelet agents for the
prevention of ischemic events in patients with acute coronary syndromes (ACS) …