Post-translational modifications (PTMs) are known to be essential mechanisms used by
eukaryotic cells to diversify their protein functions and dynamically coordinate their signaling …

Pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells is regulated
by a well characterized gene transcription circuitry. The circuitry is assembled by ESC …

Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes,
express high levels of telomerase activity, and express cell surface markers that characterize …

Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

The number of glycan determinants that comprise the human glycome is not known. This
uncertainty arises from limited knowledge of the total number of distinct glycans and glycan …

Publisher Summary Aberrant glycosylation is the most common phenomenon associated
with oncogenic transformation expressed in cell membranes of animal and human cancer …

The human embryonal carcinoma cell lines NT2 D1 and NT2 B9, clonally derived from Tera-
2, differentiate extensively in vitro when exposed to retinoic acid. This differentiation is …

Conspectus The development of anticancer vaccines requires the identification of unique
epitope markers, preferably expressed exclusively on the surface of cancer cells. This …

Two monoclonal antibodies (MC631 and MC813‐70) raised against 4‐to 8‐cell stage
mouse embryos and a human teratocarcinoma cell line, respectively, detect the stage …

This review summarizes present knowledge of the chemistry of histo-blood group ABH and
related antigens. Recent advances in analytical carbohydrate chemistry (particularly mass …