Purpose The present review article focuses on highlighting the main technologies used as
tools that improve the delivery of transdermal biomolecules, addressing them from the point …

Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …

Psoriasis is a condition of the skin which involves scales, dry patches, and inflammation.
Methotrexate (logP:− 1.8, MW: 454.44 g/mol) is administered orally or intravenously to treat …

Background A plethora of research has explored the potential of bioactive peptide as a new
class of drug therapeutics, yet only a minute amount has successfully translated into clinical …

Skin is the largest external organ in the human body but its use for therapeutic purposes has
been minimal. Stratum corneum residing on the uppermost layer of the skin provides a tough …

Many biological molecules have been passed through the skin to treat diseases. In recent
decades, the use of phospholipid nanocarriers has been considered as a tool to increase …

Peptides and proteins are gaining increasing importance as therapeutic agents. Oral
delivery of these molecules is not feasible due to gastrointestinal degradation. Parenteral …

Abstract HR9 (Ac-HYWRELQYR-NH2) is an innovative and proprietary peptide designed to
ameliorate skin disorders mediated by neuronal exocytosis. Its topical delivery guarantees …

Reverse electrodialysis (RED) technology generates energy from the salinity gradient by
contacting waters with different salinity. Herein, we develop the disposable skin patch using …