Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

Multiple sclerosis (MS) is a disease of the central nervous system characterized by
inflammation, demyelination, and neuronal damage. Environmental and genetic factors are …

Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system
commonly affecting young adults. Pathologically, there are patches of inflammation …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Epstein-Barr virus (EBV) is a ubiquitous herpesvirus strongly associated with multiple
sclerosis (MS), a chronic inflammatory disease of the central nervous system (CNS) …

Background Proposed co-factors triggering the pathogenesis of multiple sclerosis (MS) are
the Epstein Barr virus (EBV), and the potentially neuropathogenic MSRV (MS-associated …

Multiple sclerosis is associated with lesions not just in the white matter, but also involving the
cortex. Cortical involvement has been linked to greater disease severity and hence …

Highlights•Additional observations of HHV6-specific B and T cell reactivity in MS
CSF.•Evidence of correlations between HHV6 status, polymorphisms and response to …

Multiple sclerosis (MS) is one of the most common neurological disorders in young adults.
The etiology of MS is not known but it is widely accepted that it is autoimmune in nature …

Objective To determine if altered tryptophan (Trp) metabolism is associated with MS risk or
disease severity in children. Methods Participants with pediatric‐onset MS and clinically …