Cardiac diseases, such as myocardial infarction and heart failure, have become a major
clinical problem globally. The accumulating data demonstrate that bioactive compounds with …

Cardiac fibrosis constitutes irreversible necrosis of the heart muscle as a consequence of
different acute (myocardial infarction) or chronic (diabetes, hypertension,…) diseases but …

Doxorubicin (DOX) is an effective and widely used anticancer drug but has limited clinical
applicability because of its cardiotoxicity. Ferroptosis plays a key role in DOX-induced …

Abnormality in myocardial copper homeostasis is believed to contribute to the development
of cardiomyopathy. Trientine, a copper-chelating drug used in the management of patients …

Doxorubicin (DOX) is an anthracycline antibiotic widely used as a chemotherapeutic agent
to treat solid tumours and hematologic malignancies. Although useful in the treatment of …

Background Heart failure (HF) is associated with high mortality and rehospitalization rates,
highlighting the need for novel therapeutic approaches. Jianxin (JX) granules, a Traditional …

Cardiac hypertrophy is an early hallmark during the clinical course of heart failure.
Therapeutic strategies aiming to alleviate cardiac hypertrophy via the mitogen-activated …

Endothelial dysfunction is a hallmark of cardiovascular diseases, contributing to impaired
vasodilation, altered hemodynamics, and atherosclerosis progression. Trimetazidine …

The promising results obtained in the PARADIGM-HF trial prompted the approval of
sacubitril/valsartan (SAC/VAL) as a first-in-class treatment for heart failure with reduced …

Garcinia celebica L. syn. Garcinia hombroniana Pierre belongs to the family Clusiaceae, is
indigenous to Southeast Asian countries. This review aims to provide updated …