A Panorama of Extracellular Vesicle Applications: From Biomarker Detection to Therapeutics

S Das, CJ Lyon, T Hu - ACS nano, 2024 - ACS Publications
Extracellular vesicles (EVs) secreted by all cell types are involved in the cell-to-cell transfer
of regulatory factors that influence cell and tissue phenotypes in normal and diseased …

Injury minimization after myocardial infarction: focus on extracellular vesicles

L Barile, E Marbán - European Heart Journal, 2024 - academic.oup.com
Despite improvements in clinical outcomes following acute myocardial infarction, mortality
remains high, especially in patients with severely reduced left ventricular ejection fraction …

[HTML][HTML] Navigating the landscape of RNA delivery systems in cardiovascular disease therapeutics

P Gil-Cabrerizo, T Simon-Yarza, E Garbayo… - Advanced Drug Delivery …, 2024 - Elsevier
Cardiovascular diseases (CVDs) stand as the leading cause of death worldwide, posing a
significant global health challenge. Consequently, the development of innovative …

Extracellular Vesicles' Role in Angiogenesis and Altering Angiogenic Signaling

M Ateeq, M Broadwin, FW Sellke, MR Abid - Medical Sciences, 2024 - mdpi.com
Angiogenesis, the process of new blood vessels formation from existing vasculature, plays a
vital role in development, wound healing, and various pathophysiological conditions. In …

Scalable purification of extracellular vesicles with high yield and purity using multimodal flowthrough chromatography

SE Bonner, SI van de Wakker, W Phillips… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important
mediators of cell–cell communication via the transfer of bioactive content and as such they …

Effects of small extracellular vesicles derived from normoxia- and hypoxia-treated prostate cancer cells on the submandibular salivary gland epithelium in vitro

A Špilak, A Brachner, HP Friedl, A Klepe… - Tissue …, 2024 - Taylor & Francis
Small extracellular vesicles (sEVs) are an important part of intercellular communication.
They are phospholipid bilayer particles that carry active biomolecules such as proteins …

[HTML][HTML] Recent Insights into Endogenous Mammalian Cardiac Regeneration Post-Myocardial Infarction

E Fiorino, D Rossin, R Vanni, M Aubry… - International Journal of …, 2024 - mdpi.com
Myocardial infarction (MI) is a critical global health issue and a leading cause of heart
failure. Indeed, while neonatal mammals can regenerate cardiac tissue mainly through …

The Dual Role of Small Extracellular Vesicles in Joint Osteoarthritis: Their Global and Non-Coding Regulatory RNA Molecule-Based Pathogenic and Therapeutic …

Z Li, R Bi, S Zhu - Biomolecules, 2023 - mdpi.com
OA is the most common joint disease that affects approximately 7% of the global population.
Current treatment methods mainly relieve its symptoms with limited repairing effect on joint …

Vericiguat enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction through microRNA-1180-3p/ETS1 pathway

C Li, C Zheng, Y Pu, H Zhou, Y Li, W Wang, X Chen… - Cellular …, 2025 - Elsevier
Reversing cardiac fibrosis contributes to the restoration of cardiac function in acute
myocardial infarction (MI). Exosomes-derived mesenchymal stem cells (MSCs) have been …

Engineering extracellular vesicles for targeted therapeutics in cardiovascular disease

E Fu, K Pan, Z Li - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Extracellular vesicles (EVs) are nanosized particles secreted by cells that play crucial roles
in intercellular communication, especially in the context of cardiovascular diseases (CVDs) …