Intermolecular carboamination of olefins with general alkyl groups is an unsolved problem.
Diastereoselective carboamination of acyclic olefins represents an additional challenge in …

Oxazolidines, derived from widely available enantiomerically pure 1, 2‐aminoalcohols, are
versatile chiral auxiliaries for several key transformations, often serving as a platform for …

The first examples of cobalt-catalyzed multicomponent couplings of mixed aromatic arylzinc
reagents with Michael acceptors and carbonyl compounds or imines is described. The …

A copper catalyzed asymmetric tandem double Michael addition of diethylzinc to α, β-
unsaturated ketones followed by trapping with nitroolefins has been developed using chiral …

We demonstrate that α-(aminomethyl) acrylates are suitable acceptors for 1, 4-additions of
dialkylzincs in aerobic conditions. The air-promoted radical–polar crossover process …

We describe here an asymmetric aldol reaction based on the principle of Memory of
Chirality. From α‐amino acids such as leucine and methionine, we have synthesized in two …

Abstract" Rosen y colaboradores, en 1993, reportaron la primera síntesis racémica del
receptor antagonista CP-99,994 en nueve etapas de reacción a partir de 1, 3, 5 …

β-Alkoxycarbonyl-γ-lactams and γ-alkoxycarbonyl-δ-lactams were synthesized via a
conjugate alkylation/Mannich reaction/lactamization tandem reaction of unsaturated …

En el presente trabajo se han desarrollado estrategias de síntesis que involucran la
presencia de auxiliares quirales heterocíclicos de cinco miembros, oxazolidinas y …