Metabonomics of human colorectal cancer: new approaches for early diagnosis and biomarker discovery

Y Ni, G Xie, W Jia - Journal of proteome research, 2014 - ACS Publications
Colorectal cancer (CRC) is one of the most common cancers in the world, having both high
prevalence and mortality. It is usually diagnosed at advanced stages due to the limitations of …

Metabolomics of colorectal cancer: past and current analytical platforms

MD Williams, R Reeves, LS Resar, HH Hill - Analytical and bioanalytical …, 2013 - Springer
Metabolomics is coming of age as an important area of investigation which may help reveal
answers to questions left unanswered or only partially understood from proteomic or …

Serum amino acid profiles and their alterations in colorectal cancer

AB Leichtle, JM Nuoffer, U Ceglarek, J Kase, T Conrad… - Metabolomics, 2012 - Springer
Mass spectrometry-based serum metabolic profiling is a promising tool to analyse complex
cancer associated metabolic alterations, which may broaden our pathophysiological …

Feasibility of MR metabolomics for immediate analysis of resection margins during breast cancer surgery

TF Bathen, B Geurts, B Sitter, HE Fjøsne, S Lundgren… - PloS one, 2013 - journals.plos.org
In this study, the feasibility of high resolution magic angle spinning (HR MAS) magnetic
resonance spectroscopy (MRS) of small tissue biopsies to distinguish between tumor and …

Follicular Adenomas Exhibit a Unique Metabolic Profile. 1H NMR Studies of Thyroid Lesions

S Deja, T Dawiskiba, W Balcerzak… - PloS one, 2013 - journals.plos.org
Thyroid cancer is the most common endocrine malignancy. However, more than 90% of
thyroid nodules are benign. It remains unclear whether thyroid carcinoma arises from …

Altered tissue metabolites correlate with microbial dysbiosis in colorectal adenomas

JL Nugent, AN McCoy, CJ Addamo, W Jia… - Journal of proteome …, 2014 - ACS Publications
Several studies have linked bacterial dysbiosis with elevated risk of colorectal adenomas
and cancer. However, the functional implications of gut dysbiosis remain unclear. Gut …

Characterizing metabolic changes in human colorectal cancer

MD Williams, X Zhang, JJ Park, WF Siems… - Analytical and …, 2015 - Springer
Colorectal cancer (CRC) remains a leading cause of cancer death worldwide, despite the
fact that it is a curable disease when diagnosed early. The development of new screening …

Distinct metabolomic profiles of papillary thyroid carcinoma and benign thyroid adenoma

Y Xu, X Zheng, Y Qiu, W Jia, J Wang… - Journal of proteome …, 2015 - ACS Publications
Papillary thyroid carcinoma (PTC) and benign thyroid adenoma (BTA) are the most common
head and neck tumors. However, the metabolic differences between PTC and BTA have not …

Metabolomic analysis of percutaneous fine-needle aspiration specimens of thyroid nodules: Potential application for the preoperative diagnosis of thyroid cancer

I Ryoo, H Kwon, SC Kim, SC Jung, JA Yeom, HS Shin… - Scientific reports, 2016 - nature.com
Thyroid nodules are a very common problem. Since malignant thyroid nodules should be
treated surgically, preoperative diagnosis of thyroid cancer is very crucial. Cytopathologic …

Metabolomics approach to thyroid nodules: A high-resolution magic-angle spinning nuclear magnetic resonance–based study

P Miccoli, L Torregrossa, L Shintu, A Magalhaes… - Surgery, 2012 - Elsevier
Background Proton magnetic resonance spectroscopy of operative specimens has been
reported to successfully differentiate normal tissue from malignant thyroid tissue. We used a …